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Volume 4 Endocrinology & Diabetes Research
Page 26
Notes:
conferenceseries.com
October 01-02, 2018 Osaka, Japan
12th International Conference on
Endocrinology, Diabetes and Metabolism
Endocrinology Summit 2018
October 01-02, 2018
Using math-physical medicine to study the probability of having a heart attack or stroke based on combination of
metabolic conditions, lifestyle, andmetabolism index
Background & Aim: The author has extended his 8-year T2D research along with ~1.5M data to examine the relationship
among metabolic conditions, lifestyle, metabolism index, and the probability of having a heart attack or stroke.
Material & Methodology: In 2014, he researched and built a metabolism model to measure the multiple interactions of
four metabolic disease outputs and six lifestyle inputs. Initially, he chose age, gender, race, family history, smoking, drinking,
substance abuse, personal medical history and waistline to establish a "static'' baseline. He then applied the hemodynamics
concept to develop a dynamic macro-simulated model for blood blockage and artery rupture. He utilized 368,513 data which
include 72,893 "metabolic" conditions (obesity, diabetes, hypertension, hyperlipidemia) and 295,620 lifestyle conditions
(food, exercise, water, sleep, stress, daily life routine) within 2,274 days (1/2012-3/2018) to compute three different sets of risk
probabilities separately. Finally, he integrated them into one overall risk probability. He also conducted sensitivity analyses to
cover the probability variance by using different Weighting Factors (WF).
Results: The risk probabilities are 74% in 2000 (followed by three cardiac episodes 2001-2006) From 69% in 2012 decrease to
26.4% in 2017 (compatible with 26.7% by Framingham Study) WF sensitivity: 10% to 18%.
Conclusion: The mathematical simulation results are validated by past 17-years health examination reports. This big data
dynamic simulation approach using math-physical medicine will provide an early warning to patients with chronic disease of
having a heart attack or stroke in the future.
Biography
Gerald C Hsu has completed his PhD in Mathematics and majored in Engineering at MIT. He attended different universities over 17 years and studied seven
academic disciplines. He has spent 20,000 hours in T2D research. First, he studied six metabolic diseases and food nutrition during 2010-2013, then conducted
research during 2014-2018. His approach is "math-physics and quantitative medicine" based on mathematics, physics, engineering modeling, signal processing,
computer science, big data analytics, statistics, machine learning and AI. His main focus is on preventive medicine using prediction tools. He believes that the
better the prediction, the more control you have.
Gerald C Hsu
EclaireMD Foundation, USA
Gerald C Hsu, Endocrinol Diabetes Res 2018, Volume 4
DOI: 10.4172/2470-7570-C3-013