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conferenceseries
.com
Volume 05
Neonatal and Pediatric Medicine
ISSN: 2572-4983
World Pediatrics 2019
December 04-05, 2019
December 04-05, 2019 | Barcelona, Spain
32
nd
World Pediatrics Conference
Fatal meliodosis in siblings
Sanjay H R, K Varadaraj Shenoy, Anil Shetty, Praveen, Zohara Parveen
and
Sujonitha John
Father Muller Medical College, India
Introduction
: Melioidosis is an infection caused by gram negative bacterium,
Burkholderia pseudomallei
. In 2015, it
is estimated that there may have been 1,65,000 melioidosis cases globally, with 89000 deaths. The predominant mode
of transmission is percutaneous inoculation during exposure to soil or contaminated water.
Case series
: Case 1: A six month old female child presented with complaints of fever, cough, hurried breathing and
convulsion. On examination child was irritable, tachypnoeic with chest wall retractions and rhonchi. Child was not
maintaining saturation at room air. Lab investigations showed leucopenia and elevated CRP. Chest X-ray - opacity in
left midzone. Child had 2 more episodes of convulsions, loaded on anticonvulsants and IV antibiotics were started.
Child went to refractory shock the following day and sudden cardiac arrest, could not be revived. Blood culture
report showed growth of
Burkholderia pseudomallei
; Case 2: Four year old male child, elder sibling of the same
child, presented with fever since 3 days. On examination child was tachypnoeic, tachycardic, maintaining saturation
at room air. Mild icterus was present. Lab investigations showed elevated CRP. Chest X-ray was normal. On day
2 fevers persisted, icterus increased, child went into shock with increased work of breathing. IV antibiotics were
hiked up. Despite all resuscitative measures, child could not be revived. Blood culture report showed the growth of
Burkholderia pseudomallei
.
Conclusion
: Meliodosis is commonly seen in adults, its presentation in infants is rare. Most common clinical
manifestations are pneumonia and localized skin infection. Probable route of infection in case 1 may be from aerosols
(presence of sprinkler system in the vicinity of the house). Culture is the mainstay of diagnosis. IV ceftazidime is
the drug of choice. Consuming safe drinking water and avoiding contact with wet soil plays an important role in
preventing spread of meliodosis.
Biography
Sanjay H R is a Resident in the Department of Pediatrics in Father Muller Medical College, Mangalore, India. He graduated from the prestigious JJM Medical
College, Davangere, India before finding Pediatrics as his calling. He has also served as a Chief Medical Officer in a community health center. His current
research pursuit is his thesis on Neonatal hypoglycemia and Persistent pulmonary hypertension in newborns.
Sanjay H R et al., Neonat Pediatr Med 2019, Volume: 05