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Volume 9 Journal of Community Medicine & Health Education Public Health Congress 2019
May 15-16, 2019
May 15-16, 2019 Singapore
7th World Congress on
Public Health, Nutrition & Epidemiology
Joanna Hołowko et al., J Community Med Health Educ 2019, Volume 9
DOI: 10.4172/2161-0711-C3-060
The role of calorie restriction diet on the fatty acid profile and eicosanoids concentration
Joanna Hołowko, Maja Czerwińska Rogowska, Dominika Maciejewska, Karina Ryterska, Karolina Jakubczyk, Daniel Styburski, Joanna Palma and
Ewa Stachowska
Pomeranian Medical University, Poland
The aim of the study was to investigate the efficacy of 6 week, 2 types of diets: -500 kcal/day Caloric Restriction Diet (CR I)
with an -800 kcal/day Caloric Restriction Diet (CR II) on the fatty acid profile and eicosanoids (hydroxyoctadecadienoic
acids and hydroxyeicosatetraenoic acids) concentration. The study enrolled 94 Caucasian former athletes aged 20-42 who had
not been active for at least five years. There were three intervention groups: CR I group (n=32), CR II group (n=34), control
group (n=28). In order to evaluate the effect of diet intervention, the following variables were measured: Anthropometrics,
basic biochemical variables, fatty acids and their blood derivatives profiles. The CR II group showed significantly lower levels
of BMI, total cholesterol LDL, TG, total lipids, insulin and HOMA-IR (p<0.05). Subjects consuming the CR I diet significantly
decreased their BMI and the level of total lipids (p<0.05). The CR II group had a significantly decreased EPA level (p<0.05).
The CR I group showed a significantly increased level of the DHA (p<0.05) and improvement in the omega-3 index (p<0.05).
These subjects also showed significantly lower concentrations of 15-hydroxyicosatetraenoic acid (15-HETE). Within short
time, calorie restriction (-800 kcal) helps to improve lipid variables and insulin resistance. The CR I diet seems to be more
advantageous in the decrease of inflammation but does not improve basic biochemical variables. We can conclude that calorie
restriction can be a good choice for former athletes, although EPA and DHA supplementation is needed.
Biography
Joanna Hołowko is a PhD student of Pomeranian Medical University in Szczecin, Poland. She is currently working as a Dietician in Rehabilitation Hospital of Saint
Charles Borromeo in Szczecin. She has published seven papers in reputed journals.