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Volume 8 Journal of Community Medicine & Health Education Public Health Congress 2018
July 23-24, 2018
July 23-24, 2018 Melbourne, Australia
5th World Congress on
Public Health, Nutrition & Epidemiology
Risk factors for bacteremia in severely malnourished pneumonic children and their outcome
Abu Sadat Mohammad Sayeem Bin Shahid, Tahmeed Ahmed, K M Shahunja and Mohammod Jobayer Chisti
International Centre for Diarrhoeal Disease Research, Bangladesh
Statement of the Problem: Bacteremia is quite common in Severe Acute Malnourished (SAM) children with pneumonia, who often
experience a fatal outcome, especially in developing countries. There is limited information in the medical literature on the risks
of bacteremia in SAM children with pneumonia. We have examined the factors associated with bacteremia and their outcome in
under-five children who were hospitalized for the management of pneumonia and SAM.
Methodology & Theoretical Orientation: In this unmatched case-control study, SAM children of either sex, aged 0-59 months,
admitted to the Dhaka Hospital of the International Centre for Diarrheal Disease Research, Bangladesh (ICDDR, B) with cough
or respiratory distress and radiological pneumonia during April 2011 to July 2012 were enrolled (n=405). Those with pneumonia
as well as bacteremia constituted the cases (n=18) and randomly selected SAM children with pneumonia without bacteremia
constituted controls (n=54).
Findings: A wide range of bacterial pathogens were isolated among the cases of which 13 (72%) were gram negatives. Death rate
was higher among the cases than the controls (28% vs. 9%) but the difference was not statistically significant (p=0.111). In logistic
regression analysis, after adjusting for potential confounders, such as the lack of DPT/oral polio/HIV/hepatitis vaccination, measles
vaccination, vomiting and clinical dehydration (some/severe) the SAM children with pneumonia as well as bacteremia more often
had the history of lack of BCG vaccination (95% CI=1.17-29.98) and had diastolic hypotension (<50 mm of Hg) (95% CI=1.01-
12.86) not only after correction of dehydration but also in its absence.
Conclusion & Significance: The results of our study suggested that history of lack of BCG vaccination and presence of diastolic
hypotension in absence of dehydration on admission are the independent predictors of bacteremia in SAMchildren with pneumonia.
The results indicated the importance of continuation of BCG vaccination is to produce benefits beyond the primary benefits.
Biography
Abu Sadat Mohammad Sayeem Bin Shahid has his experience in public health especially in nutrition and other emerging problems like childhood TB and
pneumonia in developing world. He has been involved in different epidemiological research starting from observational study to clinical trial for the last 8 years. He
also published his different work in different journals.
Abu Sadat Mohammad Sayeem Bin Shahid et al., J Community Med Health Educ 2018, Volume 8
DOI: 10.4172/2161-0711-C3-038