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International Journal of Emergency Mental Health and Human Resilience | ISSN: 1522-4821 | Volume: 20
July 25-26, 2018 | Vancouver, Canada
Psychiatric & Mental Health Nursing
14
th
World Congress on
Mental Health and Wellbeing
5
th
World Congress on
&
Weight loss and associated factors among head and neck cancer patients undergoing particle therapy
Hongwei Wan
Shanghai, China
W
eight loss occurs frequently among patients with head and neck cancer during conventional radiotherapy. However, the impact
of particle therapy on weight loss has not been examined among this population. The aim of this study is to evaluate the weight
lost among patients with head and neck cancer during particle therapy, and investigate its associated factors. 126 adult patients
who received particle therapy were included. Multiple linear regressions were used to analyze the related factors for percentage of
weight loss during particle therapy. Related factors included gender, age, Karnofsky performance status (KPS), tumor location, stage,
recurrence, treatment modality, total dose on the primary tumor, concurrent chemotherapy, prior treatment, pre-treatment BMI and
nutrition risk, and total score of toxicity during particle therapy. Overall, critical weight loss occurred in 20% of the patients, and
the mean weight loss was 1.4kg (2%) during particle therapy. None of acute toxicities were greater than Grade 2, except for Grade
3 oral mucositis in 7.1% of the patients. Results of multiple linear regression indicated that only radiotherapy modality (95% CI:-
7.934--2.917, P<0.001) and total toxicity score (95% CI: -1.348--0.449, P<0.001) were significantly related to percentages of weight
loss during particle therapy among head and neck cancer patients. Thought weight loss and toxicities were less severe during particle
therapy, it is crucial that early nutrition intervention should be implemented for patients with combined particle and photon therapy,
or severe toxicities, who were in the high risk of weight loss.
Hong_whw@aliyun.comIJEMHHR 2018, Volume: 20
DOI: 10.4172/1522-4821-C3-018