pediatric-gastroenterology-digestive-diseases-2018-keynote

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Volume 8 Journal of Gastrointestinal & Digestive System
ISSN: 2161-069X
Page 10
Notes:
October 22-23, 2018 Berlin, Germany
&
JOINT EVENT
3rd International Conference on
Digestive and Metabolic Diseases
Pediatric Gastroenterology Hepatology & Nutrition
Pediatric Gastro 2018
Digestive Diseases 2018
October 22-23, 2018
13th International Conference on
Aflatoxin B1 and glucose-6-phosphate dehydrogenase deficiency in neonatal jaundice
Background: Neonatal jaundice is a major health problem in tropical regions. Severe jaundice with kernicterus was recorded
as a common cause of neonatal death.
Aim: This study was set out to detect the prevalence of aflatoxin B1 (AFB1) and glucose-6-phosphate dehydrogenase deficiency
in the sera of babies suffering from neonatal jaundice.
Methods: Blood samples were obtained from 40 jaundiced neonates and their mothers, 20 non-jaundiced controls and their
mothers. Blood groups, bilirubin concentration, erythrocytes G6PD status (colorimetrically) and AFB1 concentration by
(HPLC) in the blood were measured.
Results: In this study, AFB1 was detected in 50% of jaundiced neonates as compared with 20% of controls (x2 = 5.0, p=0.025).
It was also detected in 35% of mothers of jaundiced neonates compared with 10% of control mothers (x2 = 4.261; p = 0.039)
while, 47.5% of jaundiced neonates were G6PD deficient, compared with 15% of controls (x2= 6. 065; p= 0.014).
Conclusion: Analysis of these data showed that the presences of AFB1 and/or G6PD deficiency are risk factors for neonatal
jaundice in Egypt.
Biography
Dr Nermin has completed her MD-PhD at age of 36 from Basel University, Switzerland and presently the assistant professor of Medical Biochemistry and Molecular
Biology at Zagazig University School of Medicine, Egypt. She is also the director of Molecular Biology and Cell Culture Lab at the department, Head of Cell culture unit of
Scientific and Medical Research centre, the director of Project Management Unit, the admin of Institutional Review Board and a member of Scientific research council at
Zagazig University School of Medicine, Egypt. She have published more than 30 papers in reputed journals and participated in more than 30 in ternational conferences.
Nermin Raafat
Zagazig University, Egypt
Nermin Raafat, J Gastrointest Dig Syst 2018, Volume 8
DOI: 10.4172/2161-069X-C7-081