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Volume 08 Journal of Alzheimers Disease & Parkinsonism Parkinsons Congress 2018
May 14-15, 2018
May 14-15, 2018 Singapore
4th Global Experts Meeting on
Parkinson’s & Movement Disorders
Deep brain stimulation in parkinson’s disease: Review and update
Harini Sarva1, 2
1Weill Cornell Medicine, USA
2NY Presbyterian Hospital, USA
Deep brain stimulation has revolutionized parkinson’s disease management since its inception nearly two decades ago.
Various studies have reported its efficacy in treating the motor symptoms of PD with benefits lasting for years, primarily
with regards to tremor, rigidity and bradykinesia. Although non-motor symptoms and gait are not well treated with subthalamic
nucleus or pallidal stimulation, DBS plays a major role in improving the quality of life of individuals with advanced PD,
characterized by Levodopa-induced motor fluctuations and dyskinesia. In addition, there is an impetus for earlier implantation
and treatment with DBS as stimulation along with medical management has been shown to be more advantageous when
compared with best medical management alone. Although, the entire mechanism of action of DBS is not understood, its
potential role in treating aberrant neuronal firing is an exciting concept and has fostered research into newer technologies and
continuous loop stimulation. While the risk of hemorrhage and infection are low they are not negligible and likely represent
cumulative data over the last 20 years. This talk will review appropriate patient selection, current studies, newer targets and
upcoming technological advances in DBS for PD.
Biography
Harini Sarva is a trained fellow and Movement Disorders Neurologist, currently the Clinical Director of the Weill Cornell Parkinson’s Disease and Movement
Disorders Institute. She is the Lead Neurologist of DBS program. She has authored and co-authored several peer-reviewed papers and presented her work at
national and international conferences. She is presently working on the use of wearable devices to better enhance the evaluation of DBS patients.
Harini Sarva, J Alzheimers Dis Parkinsonism 2018, Volume 8
DOI: 10.4172/2161-0460-C2-039