ophthalmology-2016_posters-accepted-abstracts

31 / 37

Page 109
conferenceseries.com
Ophthalmology 2016
November 21-23, 2016
November 21-23, 2016 Dubai, UAE
10th International Conference on
Clinical & Experimental Ophthalmology
Volume 7 Issue 9 (Suppl) J Clin Exp Ophthalmol
ISSN: 2155-9570 JCEO, an open access journal
J Clin Exp Ophthalmol 2016, 7:9(Suppl)
Three-year outcomes of canaloplasty for the treatment of open-angle glaucoma
Mahmoud Khaimi1, 2
1Dean McGee Eye Institute, USA
2University of Oklahoma, USA
Purpose: To investigate the long term safety and efficacy outcomes of canaloplasty for the treatment of open-angle glaucoma (OAG).
Setting: Dean McGee Eye Institute, United States of America.
Methods: This nonrandomized, single center, retrospective study explored the effect of canaloplasty (as a stand-alone procedure
and combined with cataract surgery) in adult open-angle glaucoma patients. The primary endpoints investigated included mean
IOP and mean number of glaucoma medications over a 3-year period. The secondary endpoints included surgical and postsurgical
complications and secondary interventions.
Results: The study cohort included 318 subjects with a mean age of 72.5 years (range: 18.1-100 years). Mean baseline IOP for the
cohort was reported at 19.7 mmHg which was reduced to 14.4 mmHg at 12 months, 14.0 mmHg at two years and 14.7 mmHg at three
years (p<.001). Medication dependency reduced from 2.1 drops before surgery to 0.5 drops at 12 months, to 0.6 drops at two and
three years (p<0.001). The frequency of surgical and postsurgical complications was low, with no serious adverse events recorded.
Conclusion: Canaloplasty was shown to be safe and effective in achieving long-term IOP reductions and reduced dependence on
anti-glaucoma medications in the treatment of open-angle glaucoma.
The correlation between vitreomacular traction and subfoveal choroidal thickness
Igor Kozak
King Khaled Eye Specialist Hospital, KSA
Purpose: To investigate structure of vitreomacular traction (VMT), specifically, if a correlation exists between 1) the VMT type/grade
and the central foveal thickness (CFT) and subfoveal and adjacent choroidal thickness, 2) the vitreomacular/foveal angle (VMFA)
and the CFT and subfoveal and adjacent choroidal thickness, and 3) the diameter of vitreomacular adhesion (VMA) and CFT and
subfoveal and adjacent choroidal thickness.
Materials & Methods: Retrospective, multicenter image analysis study. We analyzed raster scans of the macula taken with spectral-
domain optical coherence tomography (SD-OCT) of 61 eyes of 55 patients with VMT. Conventional scans of the vitreoretinal
interface were analyzed to measure CFT and degree of VMFA. Enhanced depth imaging (EDI) scans were analyzed to measure
choroidal thickness in the macula. Multivariate test of means and t-test were used to statistical comparisons.
Results: There was no statistically significant difference in CFT between focal vs. broad and concurrent vs. isolated type VMT. Central
(p=0.009), nasal (p=0.004) and temporal (p=0.007) subfoveal choroidal thickness was significantly higher in broad VMT compared
to focal VMT. There was difference in both CFT (p=0.035) and central (p=0.005), nasal (p=0.01) and temporal (p=0.001) choroidal
thickness between moderate vs. severe VMT. There was correlation between VMFA and CFT, where a wider angle was associated with
increased CFT (p=0.026). The broader VMA was associated with increased central subfoveal (p=0.032), nasal (p=0.05) and temporal
(p=0.01) choroidal thickness.
Conclusions: Eyes with broad VMT have thicker choroid than eyes with focal VMT, which have a more open vitreomacular angle.