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Volume 8
Journal of Obesity & Weight Loss Therapy
Obesity Diet 2018
November 29-30, 2018
Page 48
Notes:
November 29-30, 2018 Bali, Indonesia
International Conference on
Obesity and Diet Imbalance
Are high protein diets effective on renal function?
Hulya Yardimci, Nazli Nur Aslan and Ayse Ozfer Ozcelik
Ankara University, Turkey
P
rotein or amino acid loading causes an increase in renal blood flow and glomerular filtration rate. Hyper filtration in
glomerular accelerates the development of chronic kidney disease. For this reason, it is thought that high protein intake may
be harmful to the kidneys. Studies on the subject have focused on the effect of protein amount and duration of consumption
on renal function. In short-term studies on hypertension, type 2 diabetes and aged people, high protein intake was found to
have an impact on glomerular filtration rate and urine albumin excretion and it was determined that this effect depends on the
age in healthy people. However, when individuals with pre-hypertension or first stage hypertension were given high protein
for six weeks, it was reported that there may be adverse effects on kidney function in long-term due to a significant increase
in cystatin. In a long-term study on adult pigs, the glomerular filtration rate was significantly higher in pigs fed with high
protein (35.0% of the energy) compared to those fed with normal protein (15.0% of the energy) at the end of the fourth month
and proteinuria was observed in pigs in the group fed with high protein. However, at the end of the eighth month, previously
observed results were not obtained between the two groups. In animal experiments, glomerular hyper filtration and fusion
have been suggested to cause glomerular injury and progressive chronic nephropathy. In another study, creatinine clearance
increased by 5-10% at 3 and 12 months in healthy individuals who consumed a high protein diet for two years. The increase in
obesity rate has been used for many years with the positive effect of high protein diets on body weight loss. However, besides
there are not certain data on the effects of high protein diets, there is no universally accepted definition for high protein intake
and long-term human intervention studies are limited. It is believed that there is a need for new studies to address concerns
about this issue.
Biography
Hulya Yardimci has completed her PhD from Ankara University, Turkey. She has published more than 40 papers in reputed journals. She has worked in the Ministry
of Health for 23 years.
hulyardimci@gmail.comHulya Yardimci et al., J Obes Weight Loss Ther 8, Volume 8
DOI: 10.4172/2165-7904-C11-088