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Volume 8

Journal of Obesity & Weight Loss Therapy

Obesity Diet 2018

November 29-30, 2018

Page 48

Notes:

November 29-30, 2018 Bali, Indonesia

International Conference on

Obesity and Diet Imbalance

Are high protein diets effective on renal function?

Hulya Yardimci, Nazli Nur Aslan and Ayse Ozfer Ozcelik

Ankara University, Turkey

P

rotein or amino acid loading causes an increase in renal blood flow and glomerular filtration rate. Hyper filtration in

glomerular accelerates the development of chronic kidney disease. For this reason, it is thought that high protein intake may

be harmful to the kidneys. Studies on the subject have focused on the effect of protein amount and duration of consumption

on renal function. In short-term studies on hypertension, type 2 diabetes and aged people, high protein intake was found to

have an impact on glomerular filtration rate and urine albumin excretion and it was determined that this effect depends on the

age in healthy people. However, when individuals with pre-hypertension or first stage hypertension were given high protein

for six weeks, it was reported that there may be adverse effects on kidney function in long-term due to a significant increase

in cystatin. In a long-term study on adult pigs, the glomerular filtration rate was significantly higher in pigs fed with high

protein (35.0% of the energy) compared to those fed with normal protein (15.0% of the energy) at the end of the fourth month

and proteinuria was observed in pigs in the group fed with high protein. However, at the end of the eighth month, previously

observed results were not obtained between the two groups. In animal experiments, glomerular hyper filtration and fusion

have been suggested to cause glomerular injury and progressive chronic nephropathy. In another study, creatinine clearance

increased by 5-10% at 3 and 12 months in healthy individuals who consumed a high protein diet for two years. The increase in

obesity rate has been used for many years with the positive effect of high protein diets on body weight loss. However, besides

there are not certain data on the effects of high protein diets, there is no universally accepted definition for high protein intake

and long-term human intervention studies are limited. It is believed that there is a need for new studies to address concerns

about this issue.

Biography

Hulya Yardimci has completed her PhD from Ankara University, Turkey. She has published more than 40 papers in reputed journals. She has worked in the Ministry

of Health for 23 years.

hulyardimci@gmail.com

Hulya Yardimci et al., J Obes Weight Loss Ther 8, Volume 8

DOI: 10.4172/2165-7904-C11-088