medical-imaging-2016_scientifictracks-abstracts

27 / 28

Notes:
Page 56
Medical Imaging 2016
October 20-21, 2016
Volume 5, Issue 5(Suppl) OMICS J Radiol
ISSN: 2167-7964 ROA, an open access journal
conferenceseries .com
October 20-21, 2016 Chicago, USA
International Conference on
Medical Imaging & Diagnosis
Svjetlana Jefic, OMICS J Radiol 2016, 6:5(Suppl)
Demyelinating diseases of the central nervous system (CNS)
Svjetlana Jefic
University Clinical Centre of Repablic of Srpska, Bosnia and Herzegovina
Demyelinating diseases (DD) of the CNS include a broad spectrum of CNS disorders that can be diagnosed relatively
routinely in some circumstances, but very challenging in other situations. Clinical course and morphological features
of these conditions may be considerable overlapping that can lead to clinical uncertainty and misdiagnoses. DD can be
primary – idiopathic inflammatory demyelinating disorders (IIDDs) and secondary – superimposed to other pathological
entities. Primary IIDDs include: Multiple sclerosis (MS), clinically isolated syndrome (CIS), neuromyelitis optica (NMO),
acute disseminated encephalomyelitis (ADEM), tumefactive demyelinating lesions (TDL), transverse myelitis (TM), chronic
inflammatory demyelinating polyneuropathy (CIDP), and Guillian-Barre Syndrome (GBS). The differentiation between them
has important implications on their managment and diagnostic road contains clinical, laboratory and neuroradiological
findings. In diagnostic complexity of the IIDDs there is an effort to find typical clinical, immunopathogenic and imaging
features playing role of biomarkers that could improve accuracy of diagnose. Identification of specific imunopathogenic and
neuroradiological profile should enable induvidualized differential diagnosis and tailored treatment in a given patient. MR
imaging is incorporated in whole diagnostic criteria and protocols of the managing IIDDs with increasing of its importance
over the time, not only in diagnostic aspect, but also researching. In everyday practice, MR is unique diagnostic tool that is
helpful in: 1. Distinguishing IIDDs from other pathological entities - (e.g., tumoral or infections lesions) avoiding unnecessary
aggressive diagnostic or therapeutic procedures; 2. Differentiation between different type of IIDDs which can provide
appropriate therapy - for instance certain patients with NMO may not response well, or even deteriorate under some of the
first-line treatment for MS; 3. Prognostic aspect – e.g. contribution to the identification of the patients with CIS or RIS who are
at greater risk for disability progression or, on the other hand, will have a more benign course; 4. Understanding tissue changes
during progression and remission – while the autopsy and anatomical observations - as a snapshot - do not explain adequately,
e.g., the recovery seen in some MS patients, MRI imaging is better to follow the tissue changes caused by demyelination. The
lecture is designed as a review of practical pearls and pitfalls of the IIDDs by presenting cases from everyday practice.
Biography
Svjetlana Jefic works as Radiologist at Department of Clinical Radiology, University Clinical Centre of Repablic of Srpska, Banja Luka, Bosnia and Herzegovina.
She is general Radiologist with completed training in fluoroscopy, x-ray exams, ultrasound, CT and MRI with focus on cross sectional imaging and with main
interest in neuroradiology as well as pathology of head and neck. Also, she had an experience in Family Medicine Practice certified by Queens University, Toronto,
Canada and Medical University of Banja Luka. She is trained on numerous radiological and neuroradiological courses (ESOR Galen Foundation courses, 1st, 2nd,
3th Schools of Neuroradiology, MRI Schools of Novi Sad, Sarajevo etc.), published four abstracts (oral presentations and e-posters at Congres of Radiologists
of Serbia and 39th Annual Meeting of ESNR), two invited lectures on BCR. Member of ESNR, ESR, Society of Radiology of BiH, Society of Radiology of Serbia.