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Volume 7, Issue 11 (Suppl)

Med Chem (Los Angeles), an open access journal

ISSN: 2161-0444

MedChem & TDD 2017

December 06-08, 2017

December 06-08, 2017 Dallas, USA

18

th

International Conference on

Medicinal Chemistry & Targeted Drug Delivery

Preclinical researches on novel sugar dendritic Gd-DTPAMRI contrast agents and IER5/Cdc25B tageted

phospha sugar antitumor agents to innovate in cancer therapy

I

nnovative and strategic materials against tumor cells to decrease sharply the number of dead people by tumors are desired

eagerly. To innovate in medical technologies of diagnosis and cure for various kinds of tumors by novel medicinal materials,

i.e., sugar dendritic Gd-DTPA complex MRI contrast agent (DEN-OH) and IER5/Cdc25B targeted novel phospha sugar

antitumor agents (TBMPP) were prepared and evaluated

in vitro

and

in vivo

methods, and then these novel medicinal materials

were revealed preclinically to have excellent characters against tumor cells.

Biography

Mitsuji Yamashita has completed his PhD from Nagoya University, Japan, and Postdoctoral studies from Toyota Science and Chemistry Research Center, Japan,

and Iowa State University, USA, as well as a Visiting Professor of University of Massachusetts, USA, and a Visiting Researcher of Oxford University, UK. He was a

Professor of Shizuoka University, Japan, and he is now a Professor, Emeritus. He has published more than 180 papers and patents.

myama44@yahoo.co.jp

Mitsuji Yamashita

Shizuoka University, Japan

Mitsuji Yamashita, Med Chem (Los Angeles) 2017, 7:11 (Suppl)

DOI: 10.4172/2161-0444-C1-035