kidney-nephrology-2017-scientifictracks-abstracts

26 / 33

Page 63
Notes:
conferenceseries.com
Volume 3, Issue 3 (Suppl) J Kidney, an open access journal
ISSN:2472-1220 Kidney & Nephrology 2017
August 28-30, 2017
August 28-30, 2017 Philadelphia, USA
15th Annual Congress on
Kidney: Nephrology & Therapeutics
Ekamol Tantisattamo, J Kidney 2017, 3:3 (Suppl)
DOI: 10.4172/2472-1220-C1-002
Hypertension after kidney transplantation: Multifactoial etiologies and transplant outcomes
Ekamol Tantisattamo
Oakland University William Beaumont School of Medicine, United States
Hypertension is one of the most common causes of cardiovascular morbidity and mortality worldwide. Several factors
contribute to the development of hypertension. Similar to non-transplant population, hypertension remains high
prevalence in kidney transplant recipients. Among kidney transplant recipients with pre-transplant hypertesion, the majority
of them still continue to be hypertensive after successful kidney transplantation; however, some kidney transplant recipients
become normotensive. Etiology of hypertension is difficulty to determined and it is likely multifactorial including genetic and
acquired conditions. Kidney is thought to be one contributing factor of hypertension and this may represent in the form of
genetic kidney disease. Native nephrectomy in non-transplant patient is one possible way tomanage uncontrolled hypertension.
Our previous data demonstrated that kidney transplant recipients who received living-unrelated renal transplantation
appeared to have lower prevalence of post-transplant hypertension compared to the recipients receiving living-related renal
transplantation. For deceased donor renal transplantation, hypertensive patients receiving kidney transplantation from the
same donor (mated kidney transplantation) seemed to convert to normotensive or remain hypertensive at the same direction.
This may implies a potential role of genetic kidney diseases. In addition to potential genetic causes of post-transplantation
hypertension, other treditional non-genetic risk factors of post-transplant hypertension are still important since these may be
reversible or preventable conditions. These common conditions or diseases include obesity. Since post-transplant hypertension
is high prevalent and crucial for kidney transplant outcomes both renal allograft and patient survivals, identifing the causes of
post-transplant hypertension should lead to strategies for preventing post-transplant hypertension and mitigate poor kidney
transplant outcomes.
Biography
Ekamol Tantisattamo has completed his MD from the Faculty of Medicine, Siriraj Hospital, Mahidol University in Bangkok, Thailand and pursued his specialty training
in internal medicine at the University of Hawaii John A Burns School of Medicine. He then completed sub-specialty training in Nephrology at Emory University
School of Medicine. Since his special interest is in clinical transplantation, he went to transplant nephrology fellowship training at Northwestern University Feinberg
School of Medicine. He is currently a staff Physician at Multi-Organ Transplant Center, Division of Nephrology, Department of Internal Medicine, William Beaumont
Hospital in Royal Oak, Michigan and Assistant Professor of Medicine at the Oakland University William Beaumont School of Medicine in Rochester, Michigan. He
is interested in clinical research in the areas of Nephrology and Transplantation including clinical hypertension, clinical pancreas-kidney transplantation, transplant
renal artery stenosis, Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) and nutrition-related post-kidney transplantation, and vascular calcification.