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Volume 6 Journal of Infectious Diseases & Therapy-Open Access Infectious Diseases Congress 2018
November 15-16, 2018
November 15-16, 2018 Istanbul, Turkey
6th Annual Conference on
Parasitology & Infectious Diseases
Co-existence of dengue fever and malaria in thrombocytopenic patients presented with acute febrile illness
Faisal Moin
Oman Medical College, Oman
Background & Aim: Dengue fever and malaria both can present with thrombocytopenia and is regarded as a strong predictor
of dengue fever. Thrombocytopenia is also considered criterion of disease severity, bad prognostic factor and its presence is
associated with increase probability of malaria. The study aims to determine frequency of co-existence of dengue fever and
malaria in thrombocytopenic patients presented with acute febrile illness in tertiary care hospital.
Method: Cross-sectional, observational study was conducted at the department of Emergency Medicine, Ziauddin University
Hospital, Karachi from April 2013 to January 2014. A total of 159 patients meeting inclusion criteria were included in this
study. 5 ml of blood by venupuncture in EDTA anti-coagulant for platelet count and preparing thick and thin films and 2 ml
of blood in plain bottle for detection of dengue specific IgM was collected from all patients. Thick films are used to identify
malarial parasites and thin films to identify specie. Dengue fever was diagnosed on positive dengue IgM. Co-existence was
labeled as positive if malarial parasites and dengue IgM found to be present at the same time. This diffusion susceptibility test
was used to determine susceptibility of bacterial agents to antibiotics. Data was analyzed by descriptive statistics using SPSS
software version 19.
Results: Overall mean (±SD) age was 38.3±7.9 years, with Male to female ratio was 1.1: 1. Coinfections (Dengue and Malaria)
were diagnosed in 5 (5.6%) of cases. From 5 cases, 3 (60%) were male and 2 (40%) were female. Mean (±SD) age of 5 positive
cases of co-infection was 37.8±8.3 years.
Conclusion: Concurrent infections were found 5.6% in this study, however, this percentage is slightly low and special
consideration should be given to the likelihood of co-infection with dengue and malaria.
Biography
Faisal Moin has completed his MBBS , FCPS (MEDICINE) from college of Physician and Surgeons, Pakistan. He is currently working as an Assistant Professor in
the Department of Medicine at National University of Health Sciences College of Medicine, Sultante of Oman
Faisal Moin, J Infect Dis Ther 2018, Volume 6
DOI: 10.4172/2332-0877-C5-051