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Volume 5, Issue 4 (Suppl) Occup Med Health Aff
ISSN: 2329-6879 OMHA, an open access journal Health Congress 2017
October 16-17, 2017
October 16-17, 2017 Dubai, UAE
12th World Congress on
Industrial Health, Healthcare and Medical Tourism
Isolation of enterococci, their antimicrobial susceptibility patterns and associated factors among
patients attending at the University of Gondar Teaching Hospital
Amelework Yilema
Ethiopia Public Health Institute, Ethiopia
Background: Enterococci become clinically important especially in immune-compromised patients and important causes of
nosocomial infections. Data on the prevalence, antimicrobial susceptibility patterns and associated factors of enterococci are
scarce in Ethiopia.
Aim & Methods: A hospital based cross-sectional study was conducted at the University of Gondar Teaching Hospital from
February 28, 2014 to May 1, 2014. Pre-tested structured questionnaire was used to collect socio-demographic data and possible
associated factors of enterococci infections. Clinical samples including urine, blood, swabs and other body fluids from patients
requested by physician for culture and antimicrobial susceptibility test during the study period were included. A total of 385
patients were included in the study. Data were entered and analyzed using SPSS Version 20. P values <0.05 were considered as
statistically significant.
Result: The overall prevalence of enterococci infection was 6.2% (24/385). The commonest sites of infections were urinary
tract followed by wound and blood. Among the 24 isolates, 33.3% (8/24) were resistant to all tested antimicrobial agents.
41.7% (10/24) of the enterococci isolates were Vancomycin resistant enterococci (VRE). Moreover, two third of the isolates
were multidrug resistant (MDR) enterococci. In multivariate analysis, duration of hospital stays for two days and more than
two days with infection rate: 17/32 (53.1%), previous history of any antibiotics (AOR= 9.13; [95% CI; 2.01-41.51], P=0.00)
and history of urinary catheterization (AOR=8.80; [95% CI; 1.70-45.64], P=0.01) were associated with presence of higher
enterococci infections than their respective groups.
Conclusion: The prevalence of enterococci infections among patients with UTIs, wound infections and sepsis were higher than
the other patients. Multi-drug resistant enterococci including VRE were isolated from clinical samples in the study area. Being
hospitalized for ≥48 hours, having history of any antibiotic administration and catheterization were associated factors for
enterococci infections. Presence of VRE indicates decreased antibiotic treatment options of multidrug resistant enterococci.
Therefore, efforts should be made to prevent enterococci infections and emergency of multidrug resistant enterococci.
Moreover, species identification and detailed study using genotypic methods are needed.
Biography
Amelework Yilema has completed her MSc in Medical Microbiology from Gondar University, Ethiopia. She is an Assistant Researcher of HIV Reference Laboratory,
has one published papers in journal and has been serving as Technical Expert.
Amelework Yilema, Occup Med Health Aff 2017, 5:4 (Suppl)
DOI: 10.4172/2329-6879-C1-037