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.com
Volume 7, Issue 3 (Suppl)
Otolaryngol (Sunnyvale), an open access journal
ISSN:2161-119X
Head, Neck and Plastic Surgery 2017
June 19-20, 2017
June 19-20, 2017 Philadelphia, USA
5
th
Global Summit and Expo on
Head, Neck and Plastic Surgery
Transcranial magnetic stimulation reveals differences between spasmodic dysphonia and muscle
tension dysphonia
Sharyl A Samargia
1
,
2
1
University of Wisconsin-River Falls, USA
2
University of Minnesota-Twin Cities, USA
Statement of the Problem:
Adductor spasmodic dysphonia (AdSD) is a form of focal dystonia resulting in a strained voice
quality during speech tasks. The pathophysiology of AdSD is largely unknown and differential diagnosis is challenging due to
the shared perceptual features with muscle tension dysphonia (MTD). Considering MTD does not have a neurologic-basis,
comparison of cortical excitability, using transcranial magnetic stimulation (TMS), between MTD and AdSD offers a novel
approach in differential diagnosis. A direct comparison of cortical excitability in AdSD and MTD has not previously been
reported.
Methodology:
10 subjects with AdSD, 8 with MTD and 10 healthy controls received single and paired pulse transcranial
magnetic stimulation (TMS) to the primary motor cortex contralateral to tested muscles, first dorsal interosseus (FDI) and
masseter. We hypothesized cortical excitability in AdSD would be significantly different than in MTD and healthy and would
correlate with perceptual severity in AdSD.
Findings:
Cortical silent period (CSP) duration in masseter and FDI were significantly shorter in AdSD than MTD and healthy
controls. Other measures failed to demonstrate differences.
Conclusion & Significance:
There are differences in intracortical excitability between AdSD, MTD and healthy controls.
Differences in intracortical inhibition in FDI and masseter suggest widespread dysfunction of the GABAB (Gamma-Amino-
Butyric Acid Type B) mechanism may be a pathophysiologic feature of AdSD, similar to other forms of focal dystonia. Further
exploration of the use of TMS to assist in the differential diagnosis of AdSD and MTD is warranted.
Biography
Sharyl A Samargia is an Associate Professor and Speech-Language Pathologist. Her expertise is the study of neuroplasticity as it relates to functional motor
recovery in individuals with neurologic disease or injury. She is interested in combining neuromodulation techniques and high intensity, task specific behavioral
practice to facilitate true neural recovery and minimize maladaptive plasticity.
sharyl.samargia@uwrf.eduSharyl A Samargia, Otolaryngol (Sunnyvale) 2017, 7:3 (Suppl)
DOI: 10.4172/2161-119X-C1-016