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Volume 8
Journal of Palliative Care & Medicine
ISSN: 2165-7386
Geriatrics 2018
July 30-31, 2018
July 30-31, 2018 | Barcelona, Spain
8
th
International Conference on
Geriatrics Gerontology & Palliative Nursing
Study of the C-reactive protein and tumor necrosis factor-α levels in the elderly before and after
resistance exercise training
Nany Hasan El Gayar
Alexandria University, Egypt
Aging results in chronic low grade inflammation that is associated with an increased risk disease, poor physical functioning
and mortality. The biomarkers that are mostly related to inflammation such as tumor necrosis factor-α (TNF α) C-reactive
protein (CRP) are created to stimulate and activate the immune system in response to inflammation. Strategies that reduce
age-related inflammation may improve the quality of life in older adults. The benefits of regular exercise for the elderly are
well established, whereas less is known on the impact of low-intensity resistance exercise on chronic low-grade inflammation
in elderly. The aim of this work was to study the level of TNF α and CRP before and after programmed resistance exercise in
elderly individuals. This study was done on thirty healthy elderly individuals aged 60 years or older of both sexes, participated in
four weeks of resistance training (RET). Circulating levels of TNF α and CRP were measured before and after exercise training.
Results of this study that both inflammatory markers TNF α and CRP, were statistically significantly decreased (P=0.036,
0.009) respectively, in comparison with the previous starting level measured before the exercise in the same individuals. There
was negative correlation between both TNF α and CRP levels and RET, which indicated that RET represents a low-cost strategy
that may reduce age-related inflammation and may thus improve the quality of life in older adults.
dr_nany_hasan@yahoo.comJ Palliat Care Med 2018, Volume 8
DOI: 10.4172/2165-7386-C2-018