gastroenterologists-2017-keynote

8 / 9

Volume 7, Issue 7 (Suppl) J Gastrointest Dig Syst
ISSN: 2161-069X JGDS, an open access journal Gastroenterologists 2017
December 14-15, 2017
Page 31
Notes:
conferenceseries.com
December 14-15, 2017 Dubai, UAE
11th World
Gastroenterologists Summit
Long-term quality of life of patients with permanent end ileostomy: Results of a nationwide cross-
sectional survey
Background: Patients with permanent end ileostomy are at high risk for detrimental stomal effects on their quality of life
(QoL). However, there are little data regarding long-term QoL in these patients.
Objective: To assess long-term QoL in patients with permanent end ileostomy.
Data Sources & Study Selection: A cross-sectional survey of 1,434 patients with permanent end ileostomy registered at the
German self-help organization, ILCO.
Main Outcome Measures: Assessment of QoL was performed according to the Short Form (SF-) 36, including physical (PCS)
and mental component summary (MCS) scores, gastrointestinal quality of life index (GIQLI) and the Cleveland global quality
of life index (CGQLI). Multivariate risk factor analysis was performed.
Results: A total of 783 responders were included. The indications for ileostomy included ulcerative colitis (44%), Crohn’s
disease (38%) and colorectal cancer (7%). Adverse effects in daily life due to stoma were reported by 72% of participants. QoL
was significantly impaired compared to the general population on all summary scores and several subscales (PCS: 44.6±10.4
(Mean±SD) vs. 50.2±10.2, P<0.001; MCS: 47.5±10.7 vs. 51.5±10.2, P<0.001; GIQLI: 94.4±16.4 vs. 126.0, P<0.001). Stoma
care problems were reported by 63% of respondents to affect QoL, including parastomal hernia (P<0.001), stenosis (P=0.003)
and prolapse (P=0.0078). Vitamin-B12, iron and zinc deficiencies were also associated with diminished QoL, with vitamin-
B12-deficiency particularly associated with reduced mental and emotional QoL. The profound negative effect of stoma care
problems and deficiencies was confirmed by multivariate analysis.
Conclusions: QoL was markedly impaired in patients with permanent end ileostomy compared to the general population.
The main reasons were stoma-associated morbidity and deficiency syndromes. These findings emphasize the importance of
prevention, screening, and adequate treatment.
Biography
Michael S Kasparek has begun his clinical and academic career at the Department of Surgery at the University of Tubingen in Germany in 2001. His research
focused on postoperative ileus and fast track surgery as well as on quality of life in patients with colorectal cancer and chronic inflammatory bowel disease. After
coming back to Germany in 2007, he continued his clinical and scientific work at the Department of Surgery at the University of Munich, Germany. In 2015 he
became the Head of the Department of Surgery of the Klinik Josephinum in Munich, Germany and continues his scientific work in collaboration with the University
of Munich.
Michael S Kasparek
University of Munich-Campus Grosshadern, Germany
Michael S Kasparek, J Gastrointest Dig Syst 2017, 7:7 (Suppl)
DOI: 10.4172/2161-069X-C1-060