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Volume 8 Journal of Gastrointestinal & Digestive System Gastro Meet 2018
August 06-07, 2018
Page 23
Notes:
conferenceseries.com
August 06-07, 2018 Abu Dhabi, UAE
Gastroenterology and Digestive
Disorders
16th International Conference on
The efficacy of bile acids in the treatment of non-alcoholic steatohepatitis:A10-year systematic review
Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the most common forms of chronic liver disease which may
progress to Non-Alcoholic Steatohepatitis (NASH). Currently there are no therapeutic strategies for such disease.
Only lifestyle modification through diet and exercise were proven to afford some benefit in patients with NAFLD. No
pharmacologic agents have so far been approved for the treatment of NAFLD or NASH. Therefore, most clinical efforts have
been directed at treating the components of metabolic syndrome, namely obesity, diabetes, hypertension and dyslipidemias.
Other interventions are directed at specific pathways potentially involved in the pathogenesis of NAFLD, such as insulin
resistance, oxidative stress, proinflammatory cytokines, apoptosis, bacterial overgrowth and angiotensin pathway. This
lecture aims to show the potential of bile acids as a promising therapeutic option for NAFLD. This is a 10-year systematic
review of the effects of bile acids on Non-Alcoholic Fatty Liver Disease (NAFLD). Bile Acids may yet prove to be an effective
targeted treatment for non-alcoholic fatty liver disease.
Biography
Higinio T Mappala is a Medical Specialist IV at the Jose Reyes Memorial Medical Center, Manila, Philippines, a Board-certified Internist, Gastroenterologist,
Endoscopist, Clinical Nutritionist and Clinical Toxicologist. He has served as a University Professor and Dean of 2 Medical Schools; a highly-regarded Researcher,
with more than 50 scientific papers and more than 20 publications. He is a former Board Director of the Philippine Societies of Gastroenterology and Digestive
Endoscopy; an online Research rater of McMaster, Canada and Online Dynamed Research peer-reviewer.
Higinio T Mappala
Jose Reyes Mem. Medical Center, Philippines
Higinio T Mappala, J Gastrointest Dig Syst 2018, Volume 8
DOI: 10.4172/2161-069X-C3-069