euro-chemistry-2017-scientifictracks-abstracts

19 / 45

Page 50
Notes:
conferenceseries.com
Volume 8, Issue 2 (Suppl) Chem Sci J 2017
ISSN: 2150-3494 CSJ, an open access journal Euro Chemistry 2017
May 11-13, 2017
May 11-13, 2017 Barcelona, Spain
4th European Chemistry Congress
Synthesis of 5-membered heterocyclic systems by the pummerer reaction
Diego Gamba-Sanchez, Juan Rueda-Espinosa and Andres Gomez-Angel
University of Los Andes, Colombia
The Pummerer reaction has been studied for many years as a powerful methot to form C-Nu bonds, its aplications in total
synthesis of natural products has been recently reviewed showing its grate potential. We recently publised a newmethod to obtain
oxaxolines by Pummerer chemistry, and the goal of the current study is to extend the scope of this methodology to the synthesis of
other heterocylcic systems. The results include approaches to pyrroles, ozaxoles, thiazoles and the application of the methodology to
the total synthesis of siphonazole and muscoride A.
Biography
Diego Gamba-Sanchez obtained his PhD in 2010 from the Ecole Polytechnique at Palaiseau. After one year as a postdoctoral associate in the laboratory of
Prof. Thorsten Bach, e moved back to Colombia ans started his independent carrier at the Universidad de los Andes in Bogotá. His research focused on new
methodologies using Pummerer chemistry and the development of synthetic routes to natural products.
Diego Gamba-Sanchez et al., Chem Sci J 2017, 8:2(Suppl)