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Clinical Pharmacology & Biopharmaceutics | ISSN : 2167-065X
Volume 7
September 18-19, 2018 | Amsterdam, Netherlands
6
th
European Biopharma Congress
Euro Biopharma 2018
Microneedles: A painless approach for enhancement of
transdermal drug delivery
M
icroneedles may be defined as needles that are 10-2000 microns in height and 10-
50 microns in width. They are available in the form of an array, which consists of
a plurality of micron-sized projections typically assembled on one side of a supporting
base or patch. Microneedles are the sharp and short needles used for enhancement of
transdermal permeation of drugs. Due to their short length, upon application, they do not
touch the nerve endings and hence are devoid of pain. Different types of microneedles
reported to enhance the transdermal permeation are solid MN, coated MN, hollowMN and
dissolving MN. Various materials ranging from metal, silicon, glass, sugars and polymers-
biodegradable and non-biodegradable have been used for fabrication of microneedles.
The present paper aims to highlight the importance and application of various types of
microneedles in transdermal drug delivery. The advantages and disadvantages of the
different types of microneedles would be discussed. Depending upon the material used
for fabrication, microneedles may be employed for rapid release or sustained release
of drug. Microneedles are particularly useful for delivery of biopharmaceuticals like
hormones, peptide and protein delivery. A case study involving the use of microneedles
for enhancement of transdermal penetration of a drug will be presented.
Biography
Hetal Thakkar is currently working as Assistant Professor at The Maharaja Sayajirao University of Baroda.
hetal_thakkar11@yahoo.comHetal Thakkar, Clin Pharmacol Biopharm 2018, Volume:7
DOI: 10.4172/2167-065X-C1-028
Hetal Thakkar
Maharaja Sayajirao University of Baroda, India