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conference

series LLC Ltd

September 18-19, 2018 | Amsterdam, Netherlands

6

th

European Biopharma Congress

Euro Biopharma 2018

Clinical Pharmacology & Biopharmaceutics | ISSN : 2167-065X

Volume 7

Page 21

Takashi Takahashi, Clin Pharmacol Biopharm 2018, Volume:7

DOI: 10.4172/2167-065X-C1-027

New synthetic technology in drug discovery

Automated synthesis and flow chemistry have attracted a great deal of attention in

recent years because these processes improve both the reproducibility and reliability

of synthesis. Development of automated synthetic procedures and storage of relevant

digital data allow anyone to reproduce the same results anytime and anywhere using

the same apparatus and reagents. As a result, synthetic chemists can spend more time

on advanced and challenging problems. Automated synthesis and flow chemistry often

enhance the safety profile of the synthetic processes. Flow chemistry is effective for the

hazardous reactions using toxic reagents or high pressure gases. Herein, we report the

automated synthesis of taxol, enediyne, lewisX and ketopiperazine analogues and the

flow synthesis of peptides and aliphatic aldehydes.

Biography

Takashi Takahashi is a Professor of Medicinal Chemistry at Yokohama University of Pharmacy, Japan. He has his

expertise in Natural Products and Medicinal Chemistry of drug development.

ttak@yok.hamayaku.ac.jp

Takashi Takahashi

Yokohama University of Pharmacy, Japan