Notes:
conference
series LLC Ltd
September 18-19, 2018 | Amsterdam, Netherlands
6
th
European Biopharma Congress
Euro Biopharma 2018
Clinical Pharmacology & Biopharmaceutics | ISSN : 2167-065X
Volume 7
Page 21
Takashi Takahashi, Clin Pharmacol Biopharm 2018, Volume:7
DOI: 10.4172/2167-065X-C1-027
New synthetic technology in drug discovery
Automated synthesis and flow chemistry have attracted a great deal of attention in
recent years because these processes improve both the reproducibility and reliability
of synthesis. Development of automated synthetic procedures and storage of relevant
digital data allow anyone to reproduce the same results anytime and anywhere using
the same apparatus and reagents. As a result, synthetic chemists can spend more time
on advanced and challenging problems. Automated synthesis and flow chemistry often
enhance the safety profile of the synthetic processes. Flow chemistry is effective for the
hazardous reactions using toxic reagents or high pressure gases. Herein, we report the
automated synthesis of taxol, enediyne, lewisX and ketopiperazine analogues and the
flow synthesis of peptides and aliphatic aldehydes.
Biography
Takashi Takahashi is a Professor of Medicinal Chemistry at Yokohama University of Pharmacy, Japan. He has his
expertise in Natural Products and Medicinal Chemistry of drug development.
ttak@yok.hamayaku.ac.jpTakashi Takahashi
Yokohama University of Pharmacy, Japan