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conferenceseries
.com
Volume 7, Issue 5 (Suppl)
Epidemiology (Sunnyvale), an open access journal
ISSN: 2161-1165
Epidemiology 2017
October 23-25, 2017
EPIDEMIOLOGY & PUBLIC HEALTH
October 23-25, 2017 | Paris, France
6
th
International Conference on
ASSOCIATION BETWEEN COGNITIVE IMPAIRMENT AND POOR ANTIHYPERTENSIVE
MEDICATIONADHERENCE IN ELDERLY HYPERTENSIVE PATIENTS
Mi Hee Cho
a
, Jae Moon Yun
a
, Ji Eun Lee
a
, Dong Wook Shin
b
and
Sang Hyuk Kim
c
a
Seoul National University Hospital, Republic of Korea
b
Samsung Medical Center, Republic of Korea
c
Seoul National University Bundang Hospital, Republic of Korea
A
dherence to antihypertensive medication is critical factor to control blood pressure and prevent complications in the
patients with hypertension. Medication management requires cognitive ability such as attention and working memory
and cognitive impairment can negatively affect medication adherence. In this study, we investigated the association of cognitive
function and antihypertensive medication adherence among the elderly hypertensive patients in Korea. This retrospective
cohort study was conducted by using the Korean National Health Insurance Service-National Sample Cohort Data of the
Elderly. Study population included the elderly who took the National Life-Transition Health Examination in 2007 and 2008.
Cognitive function was screened by Pre-screening Korean Dementia Screening Questionnaire (KDSQ-P). A cut off score of 4 or
more are subjective to further dementia screening test. Medication adherence of antihypertensive medications was calculated
based on prescription data and the cut-off values for appropriate adherence was 80%. Multivariate logistic regression analysis
was conducted to analyse association between cognitive function and medication compliance, adjusting for sex, income level,
residential area, comorbidities, and level of depression. A total of 20,303 elderly patients with hypertension were included in
the study. The prevalence of poor medication adherence of antihypertensive medications among the elderly patients was 16.5%.
Lower cognitive function was associated with poor medication adherence (Adjusted odds ratio 0.980, 95% CI 0.961-0.999 per
score). Patients with cognitive impairment are a vulnerable group to poor medication adherence. Clinicians involved in the
geriatric care should evaluate the cognitive function of the elderly thoroughly and make more efforts to educate patients with
cognitive impairment and their caregivers about the significant risk associated with inappropriate adherence. Further studies
investigating the reasons for non-adherence are needed in order to establish effective interventions for improving medication
adherence.
Biography
Mi Hee Cho graduated from School of Material Science & Engineering, Purdue University, USA with PhD degree. Later, she started studying at School of Medicine,
Pusan National University, Republic of Korea and graduated as Medical Doctor. After graduation from the medical school, she completed her residency with the
specialty of Family Medicine and presently has been working as a Fellow at Department of Family Medicine, Seoul National University Hospital, Seoul, Korea.
jom9990207@gmail.comMi Hee Cho et al., Epidemiology (Sunnyvale) 2017, 7:5(Suppl)
DOI: 10.4172/2161-1165-C1-018