epidemiology-2016_scientifictracks-abstracts

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Volume 6, Issue 5(Suppl) Epidemiology (Sunnyvale)
ISSN: 2161-1165 ECR, Open Access
Page 67
Notes:
Epidemiology 2016
October 3-5, 2016
conferenceseries.com
Epidemiology & Public HealthOctober 3-5, 2016|London, UK
4th International Conference on
NEW INSIGHTS ON REPORTING CONGENITALANOMALYRATES USING PRIMARYCARE
DATAFROMAMULTIETHNIC COHORT STUDY: THE BORN IN BRADFORD PROJECT
Chrissy Bishopa,b,c, Neil Smalla,b, Roger Parslowb,c and David Bowlesd
aUniversity of Bradford, England
bBradford Institute for Health Research, England
cUniversity of Leeds, England
dSheffield Hallam University, England
Introduction: Bradford has high rates of infant mortality for children of Pakistani origin, with Congenital Anomalies (CA)
being the most common cause of death and disability in this group. The CA rate in Bradford is higher than the national average
before age of 1 at 399 per 10,000 live births1. We linked children with CA to General Practice (GP) data, allowing prospectively
collected medical information to provide promising new insights into CA research including risk factors for CA and more
complete case ascertainment.
Methods: Of 11474 babies with questionnaire data available, children with one or more CA (n=1039) were linked to their
mothers GP data and compared to those without CA (n=10435). Diagnoses were classified using ICD-10 and validated by
clinicians. Data for case ascertainment were compared to national CA registries. We calculated univariate and multivariate risk
ratios (RRs) with 95% confidence intervals for various maternal risk factors.
Findings: The prevalence of CA was consistent to national registries for early diagnoses, but age to diagnoses was an important
factor in demonstrating increased prevalence after age 1. We found the rates slightly higher but comparable to previous rates at
461 per 10,000 live births. Only 46% of diagnoses were made before age 1, increasing significantly to 902 per 10,000 live births
up to age 8. Consanguinity was found to be a risk factor for anomalies in Pakistani mothers (multivariate RR 2.2, 95% CI 1.54-
3.03), and maternal age >34 years for White British mothers (multivariate RR 1.72, 95% CI 1.02-2.92).
Biography
Bishop worked as an Occupational Therapist for 5 years, during which she developed interests in public health and policy research. She studied her MSc in
Professional Health and Social Care whilst working in the NHS, progressing her interests towards health determinants and epidemiology. She left the NHS to
study a second MSc in Epidemiology and Biostatistics at the University of Leeds, during which was introduced to the Born in Bradford Project. On graduating she
was awarded a scholarship to study her PhD with Born in Bradford. Her special interests are pathways through care for children with complex healthcare needs.
Chrissy Bishop et al., Epidemiology (Sunnyvale), 6:5(Suppl)