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conferenceseries
.com
Volume 5, Issue 2 (Suppl)
Occup Med Health Aff, an open access journal
ISSN: 2329-6879
Environmental Health 2017
September 7-8, 2017
September 7-8, 2017 | Paris, France
Environmental Health & Global Climate Change
2
nd
International Conference on
ALLEVIATION CHRONIC CADMIUM STRESS TOXICITY IN ALBINO RATS USING SOME
DOMESTIC PLANTS
Emad Shaker
a
and
Saed Mnaa
b
a
Minia University, Egypt
b
Monofia University, Egypt
C
admium (Cd) is an environmental contaminant in air, soil, water and can induce damage to various tissues in very low
concentration. Biological experiment has been occurred to focus on Cd oxidative stress. In drinking water rat received daily
100 mg/kg body weight cadmium (CdCl
2
.2
½
H
2
O). Female rats fed standard chow diet mixed with 100 mg/kg body weight N-acetyl
cysteine (NAC) as standard protective agent. Rats in other tested groups fed chow diet mixed with 200 mg/kg body weight dried
husk tomato, nabk and sycamore in separated groups as natural edible powder plants. The toxicity of cadmium in biomedical and
histopathological analysis was investigated without and with protective powder plants compare to NAC. Four weeks experiment
showed the toxic contaminated cadmium in serum alkaline phosphatase, creatinine, malondialdehye and catalase activity beside the
histological patterns for liver, kidney, ovary and brain sections. Results showed that husk tomato poses high protective effect closed
to that for NAC in most values. Moreover, the proven potential for NAC and husk was clearly found in body weight, food efficiency
ratio, and liver and kidney disorders. The health values of lipid peroxidation and catalase activity as oxidative stress markers were
observed in NAC and husk as well. Liver tissue, the most related organ to Cd toxicity was improved in histology patterns through
NAC and husk administration.
Biography
Emad Shaker has done his PhD work in UCD, and He has done his post doctoral research in Food Science Technology at Cork, Ierland. He Identified chemical
structure of compounds and his aim is to measure the antioxidant potential effect in oxidative stress. He did his research in analyzing the biological role of extracted
natural antioxidants
in vivo
. He is presently working as a Professor of Biochemistry at Minia University, Egypt.
eshaker10@hotmail.comEmad Shaker et al., Occup Med Health Aff 2017, 5:2(Suppl)
DOI: 10.4172/2329-6879-C1-031