18
conference
series LLC Ltd
3
rd
International Conference on
3
rd
International Conference on
Ecology, Ecosystem and Conservation Biology
Microbial Ecology & Eco Systems
&
March 18-19, 2019 | Chicago, USA
Find More Information @
https://conferenceseries.com/america/MARCH 2019 Conference Series LLC Ltd
Photodynamic
therapy used to
reduce microbial
contamination and
disinfection on
solid surfaces of
diverse materials in
a sustainable and
ecological way
T
he Photodynamic Therapy
is based on the association
of a nontoxic photosensitizer
and post-irradiation with
a proper wavelength light
source proper for the
formation of reactive species
oxygen. PDT may be an
option for decontamination of
surfaces of various materials
that are based on the
interaction between a non-
toxic photosensitizer (PS) and
irradiation with a wavelength
light source suitable for the
formation of reactive oxygen
species with antimicrobial
effects. These photoreactions
have been used since the
beginning of the 20th century
as a tool to disable numerous
pathogens and were
established as a therapeutic
platform commonly referred
to as PDT. With help of
powerful and well controlled
light sources, such as lasers
and light emitting diode
(LED), great advances were
made in photochemical
and photobiotic studies
the low-intensity light can
also be associated with the
administration of nontoxic
PS to locally promote
photochemical reactions that
might induce cell death. In
short, when the PS absorbs
a photon, it is upgraded to
an excitable state and can
transfer charges or energy
to molecular oxygen of the
fundamental state inducing
the formation of reactive
species of oxygen. The
byproducts of phenothiazine,
such as toluidine blue and
methylene blue (MB) are
amongst the most studied
PS for the antimicrobial
photodynamic therapy
(aPDT) and have been
tested in the last decades in
association with the red light
to promote the bactericidal
effect
in vitro
and
in vivo
.
These results, based on
studies in the literature,
suggest good perspectives
for the formulation of
adequate clinical protocols
for microbial control and
thus, the aPDT open new
frontiers and nontoxic and
low-cost alternative for the
disinfection of biomedical
tools as non-critical
instruments, besides being
useful for the food industry.
The objective of this paper is
to demonstrate that devices
such as PID (patent deposit
MU-BR 20.2017.002297-3)
and UPID (patent deposit
MU-BR 20.2018.009356-
3) are capable of reducing
JOURNAL OF ECOSYSTEM& ECOGRAPHY 2019, VOLUME 9 | DOI: 10.4172/2157-7625-C1-043
Foggiato AA
State University of North Parana, Brazil
KEYNOTE FORUM |
DAY 1