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Volume 5, Issue 5 (Suppl)
J Neurol Disord, an open access journal
ISSN: 2329-6895
CNS 2017
October 02-03, 2017
Page 30
Notes:
conference
series
.com
3
rd
International Conference on
Central Nervous System Disorders and Therapeutics
October 02-03, 2017 Vienna, Austria
Khin Bo Maung, J Neurol Disord 2017, 5:5(Suppl)
DOI: 10.4172/2329-6895-C1-022
Multiple sclerosis, corpus callosum & bedside test
D
emyelination affects highly myelinated structures like Corpus Callosum (CC). CC is unique in function that it connects
right and left hemisphere. It synchronises bimanual or bipedal activities. Affecting CC can disturb synchrony between
the two hemispheres and will affect bimanual and bipedal tasks. The aim is to see if speed of clapping (bimanual activity) can
reflect the involvement of CC in multiple sclerosis. Consecutive 70 multiple sclerosis patients from outpatient clinics and home
visits were tested for bimanual hand function (clapping). Exclusion criteria are upper limb power <3/5 MRC scale, pain, visual
impairment, intentional tremors, stroke or cognitive impairment. Study period started from 01-09-2016. Comparison of speed
between rapid supination/pronation of left and right hand separately and then clapping of both hands (supination/pronation
of each hands alternatively). Patients had to do as fast as they could. Noticeable slowing of clapping compared to single hand
supination/pronation was taken as a sign slowing down of conduction through CC. 31 patients were excluded, 34 patients
showed no noticeable difference, 2 patients were difficult to make conclusions and 3 patients showed definite slowing down
in clapping. Positive patients will have difficulties in doing bimanual activities like using two sticks for mobility, typing using
keyboard, pushing wheel chair bimanually, etc. It is possible to detect CC involvement by doing above bedside test and can be
used in rehabilitation setting. Sample size is not large enough and larger studies are needed to validate the finding.
Biography
Khin Bo Maung is involved in Neurorehabilitation over 20 years. He is also a Lecturer (Hon) in Hull and York Medical School teaching 4th Year Medical Students in CNS
and Musculoskeletal Blocks. He is doing Botulinum Toxin injection in Spasticity, Dystonia and Involuntary Movement disorders over 15 years. He has given poster and oral
presentations in international neurorehabilitation conferences. He is also involved in using Functional Electrical Stimulation (FES) over 10 years and presented regularly in
International FES Conferences. He is working on developing Hypertonic Hand Monitoring Scale.
bokhinmaung@yahoo.co.ukKhin Bo Maung
Northern Lincolnshire and Goole Hospitals NHS Foundation Trust, UK