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Volume 2, Issue 3(Suppl) Oncol Cancer Case Rep
ISSN: 2471-8556 an open access journal
Page 63
Notes:
Cancer Therapy & Biomarkers 2016
December 05-07, 2016
conferenceseries.com
CANCER THERAPY,
BIOMARKERS & CLINICAL RESEARCH
15th World Congress on
December 05-07, 2016 Philadelphia, USA
Conclusions: These results indicate that analysis of wound tissue that would otherwise be discarded can be used as a
quantitative, accurate indicator of healing. Such an assay will be critical for employing a precision medicine approach
to wound care.
Next steps: More patients are needed to further optimize this diagnostic assay. Wound samples can be stored in a
buffer and shipped at room temperature to our lab for analysis. If you are interested in collaborating on this project.
Future directions include expanding to other wound types (combat wounds, burns, chronic venous ulcers, etc.) and
developing a rapid assay for point-of-care diagnosis. Our pilot data suggest that this method will be readily applica-
ble to burn wounds without the need for further optimization.
Citation: Nassiri, S., I. Zakeri, M.S. Weingarten, K.L. Spiller. “Relative expression of pro-inflammatory and anti-in-
flammatory genes reveals differences between healing and nonhealing human chronic diabetic foot ulcers.” Journal
of Investigative Dermatology 2015 (135) 1700-1703.
Biography
Kara received her bachelor’s and master’s degrees in biomedical engineering from Drexel University in 2007. She conducted her doctoral research
in the design of semi-degradable hydrogels for the repair of articular cartilage in the Biomaterials and Drug Delivery Laboratory at Drexel and in the
Shanghai Key Tissue Engineering Laboratory of Shanghai Jiao Tong University. After completing her PhD in 2010, when she received the award for
Most Outstanding Doctoral Graduate: Most Promise to Enhance Drexel’s Reputation, she conducted research in the design of scaffolds for bone
tissue engineering as a Fulbright Fellow in the Biomaterials, Biodegradables, and Biomimetics (the 3Bs) Research Group at the University of Minho in
Guimaraes, Portugal. She is currently conducting research in the design of immunomodularatory biomaterials, particularly for bone tissue engineering.
Her research interests include cell-biomaterial interactionns, biomaterial design, and international engineering education.
Kara L Spiller et al., Oncol Cancer Case Rep 2016,2:3(Suppl)