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Volume 3

Journal of Cancer Diagnosis

Cancer Diagnostics Conference 2018

August 15-16, 2018

August 15-16, 2018 Singapore

International Conference on Cancer Research & Diagnostics

Asia Pacific Biotechnology Congress

Joint Event on

J Cancer Diagn 2018, Volume 3

DOI: 10.4172/2476-2253-C1-003

Long-term exposure of particle matter and ozone for cancer risk according to obesity and health-

related behaviors: A nationwide population-based cross-sectional study

Kyoung Jin Kim

Konkuk University, South Korea

ong-term exposure to ambient particulate matter (PM10) and ozone (O3) has been suggested to be associated with an

increased risk of cancer. However, there is little evidence on association between cancer and air pollution according to

obesity and health-related behaviors. We selected 100,867 subjects from the 2012 Korean Community Health Survey and

socioeconomic characteristics, health-relatedbehaviors andprevious cancer historywere surveyed.Daily average concentrations

of hourly measured PM10 and O3 (2003-2012) from the Korean Air Pollutants Emission Service were obtained. The risk of

cancer for the interquartile increase of particulate matter and ozone was evaluated using multiple logistic regression analysis

according to age, obesity and health-related behaviors. PM10 and O3 were positively associated with cancer risk in univariate

analysis (PM10: Odds ratio [OR] 1.18, 95% confidence interval [CI] 1.06-1.31. O3: 1.04, 1.01-1.07). We found out the increased

risk of cancer with the obese subjects aged 50 years and older. However, we did not confirm these trends in non-obese and

alcohol status. About PM10, obese men, obese ever smoker, obese inactive subjects were associated with the increased cancer

risk. For O3, the cancer risk significantly increased in obese adults aged 50 and older, regardless of sex, smoking, alcohol

intake and physical activity. However, active subjects aged 50 and older had no significant association with cancer risk. In

conclusion, long-term exposure to ambient air pollution is associated with the risk of cancer, reinforced with obesity, smoking

and physically inactivity over 50 years old.