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conferenceseries
.com
Volume 8, Issue 4 (Suppl)
J Addict Res Ther
ISSN: 2155-6105 JART, an open access journal
Alcoholism 2017
July 03-04, 2017
July 03-04, 2017 Kuala Lumpur, Malaysia
7
th
International Conference on
Addictive Disorders and
Alcoholism
Comparison of anxiolytic effects of the homeopathic complex Vita-C 15 when compared with
Aconitum
Napellus
in the acutely stressed C57BL6 mice
Siaw Min Liew
Cyberjaya University College of Medical Sciences, Malaysia
A
nxiety, phobias and stress are the main mental health problems among the Malaysian population, with global prevalence
varying from 8% to 18%. Even so, less than 30% who suffer these disturbances seek treatment. The objective of this study is
to evaluate and compare the anxiolytic effects of
Aconitum napellus
and homeopathic complex Vita-C 15 in the acutely stressed
C57BL6 mice by using the fecal corticoid test, open field test (OFT) and c-fos, NMDAR 2B, NPY 1R and NPY 2R activity
through the hippocampus. A double blinded randomized controlled study is conducted at Animal Laboratory of Cyberjaya
University College of Medical Sciences (CUCMS). All the animals are acclimatized to constant laboratory conditions for 14
days before starting the experiments. Prior to the experiment, a pilot study is performed to identify the most suitable and
ideal potency for the homeopathic remedy of
Aconitum napellus
. The animals are tested (n=3) per group on the potency of 6
C, 30 C and 200 C. The treatments are carried out over 9 days. 48 male C57BL6 mice (n=6), 4-5 weeks of age are used. They
are randomly selected and divided into two groups. Group I is the healthy control group of mice which are not exposed to
acute stress. Group II (stress group); comprise of mice expose to acute restraint stress. Prior to restraint stress, the treatments
given are
Aconitum napellus 30
cH, Homeopathic complex Vita-C 15, Diazepam, and placebo. Then the results are evaluated
by fecal CORT test and open field test by comparing the anxiolytics between pre-test and post-test.
Aconitum napellus 30
cH
and Homeopathic complex Vita-C 15 are expected to be more effective and can reduce the occurrence of anxiety in the acutely
stressed C57BL6 mice. Thus research into prevention and supportive therapies is necessary and beneficial for this disorder.
Biography
Siaw Min Liew has her expertise in the research on anxiety, depression and stress under the treatment and management of Traditional and Complementary
Medicine (Homeopathy) and evaluation and passion in improving the mental health and wellbeing. She is currently pursuing her Postgraduate study of Master of
Medical Science (MSc) on the comparison of homeopathic and conventional intervention on anxiety and stress.
charisliew88@gmail.comSiaw Min Liew, J Addict Res Ther 2017, 8:4 (Suppl)
DOI: 10.4172/2155-6105-C1-030