

Journal of Addiction Research & Therapy
ISSN: 2155-6105
August 13-14, 2018
Madrid, Spain
Addiction Psychiatry 2018
Page 31
8
th
International Conference on
Addiction Psychiatry
A
ddiction is a serious public health problem that causes
morbidity and mortality and economic burden. Recognizing
that addiction results from the choices made by those with that
disorder, the eld of addiction science, beginning in the 21
st
century has increasingly focused its attention on decisionmaking
processes. A hallmark of addiction is the fact that the individual
suffering fromit continues tousedespitenegativeconsequences.
Progress in identifying the neurobehavioral decision processes
underlying disadvantageous decisionmaking evident in addiction
could facilitate the transition from a symptom-focused approach
to a mechanism-focused approach, and this may further the
development of treatments for these conditions. Decision-
making impairments can be both the cause and consequence of
addiction. Some of the traits linked to substance use vulnerability,
such as reward-sensitivity and impulsivity, contribute to poorer
performance in decision-making tasks. Similarly, the deleterious
effects of chronic substance use on frontostriatal and limbic
systems have been shown to produce or exacerbate impairments
in cognitive control processes that contribute to decision
making, such as working memory. This presentation will focus
on neurobehavioral theories of impaired decision-making in
addiction; impairments in three stages of decision-making in
addiction, namely, preference formation, choice implementation,
and feedback processing; and implications of impaired decision-
making in addiction.
Recent Publications
1. Bickel W K, Mellis A M, Snider S E, Athamneh L N, Stein J S
and Pope D A (2017) 21
st
century neurobehavioral theories
of decision making in addiction: Review and evaluation.
Pharmacology Biochemistry and Behavior 164:4-21.
2. Verdejo Garcia A, Lawrence A J and Clark L (2008)
Impulsivity as a vulnerability marker for substance-use
disorders: Review of findings from high-risk research,
problem gamblers and genetic association studies.
Neurosci Biobehav Rev 32(4):777–810.
3. Verdejo García A, Chong T T J, Stout J C, Yücel M and
London E D (2017) Stages of dysfunctional decision-
making in addiction. Pharmacology Biochemistry and
Behavior 164:99-105.
4. Albein Urios N, Martinez Gonzalez J M, Lozano O, Clark L
and Verdejo Garcia A (2012) Comparison of impulsivity
and workingmemory in cocaine addiction and pathological
gambling: Implications for cocaine-induced neurotoxicity.
Drug Alcohol Depend 126(1–2):1–6.
5. VonmoosM,HulkaLM,PrellerKH,MinderF,BaumgartnerM
RandQuednowBB (2014) Cognitive impairment in cocaine
users is drug-induced but partially reversible: Evidence
from a longitudinal study. Neuropsychopharmacology
39(9):2200–2210.
Biography
Ebru Aldemir has been a Psychiatrist for fifteen years. She is a Lecturer and
a PhD student on Substance Addiction Programme at Ege University Institute
on Drug Abuse, Toxicology and Pharmaceutical Science. She has published
more than 15 papers in reputed journals. Her research interests are addictive
disorders, neurocognitive functions, motivational interviewing and brief psycho-
therapies.
ozturk.ebru2000@gmail.comDecision making in addiction
Ebru Aldemir
Aegean University Institute on Drug Abuse,
Toxicology and Pharmaceutical Science, Turkey
Ebru Aldemir, J Addict Res Ther 2018, Volume 9
DOI: 10.4172/2155-6105-C2-038