Plant-Genomics-2016_Scientific-Tracks-Workshop

33 / 60

Volume 4, Issue 3 (Suppl) Adv Crop Sci Tech
ISSN: 2329-8863 ACST, an open access journal
Page 59
Notes:
Plant Genomics 2016
July 14-15, 2016
conferenceseries.com
July 14-15, 2016 Brisbane, Australia
4th International Conference on Plant Genomics
PRL1modulates root stemcell niche activity andmeristemsize throughWOX5 andPLTs inArabidopsis
Xia Li
Huazhong Agricultural University, China
The stem cell niche in the root meristemmaintains pluripotent stem cells to ensure a constant supply of cells for root growth. Despite
extensive progress, the molecular mechanisms through which root stem cell fates and stem cell niche activity are determined
remain largely unknown. In Arabidopsis thaliana, the Pleiotropic Regulatory Locus 1 (PRL1) encodes a WD40-repeat protein subunit
of the spliceosome-activating Nineteen Complex (NTC) that plays a role in multiple stress, hormone and developmental signaling
pathways. In this study, we show that PRL1 is involved in the control of root meristem size and root stem cell niche activity. PRL1
is strongly expressed in the root meristem and its loss of function mutation results in disorganization of the quiescent center (QC),
premature stem cell differentiation, aberrant cell division and reduced root meristem size. Our genetic studies indicate that PRL1 is
required for confined expression of the homeodomain transcription factor WOX5 in the QC and acts upstream of the transcription
factor PLETHORA (PLT) in modulating stem cell niche activity and root meristem size. These findings define a role for PRL1 as an
important determinant of PLT signaling that modulates maintenance of the stem cell niche and root meristem size.
Biography
Xia Li has received her PhD from Purdue University in the United States and then joined in the Vector Tobacco Inc., as a Research Scientist from 2001-2004.
In 2004, she was selected as one of the “One Hundred Talents” of Chinese Academy of Sciences (CAS) and became a Principal Investigator in the Institute of
Genetics and Developmental Biology, CAS. She has moved to Huazhong Agricultural University as Professor since September, 2015. She has published more than
50 papers in reputed journals and has been serving as an Editorial Board Member of repute.
Xia Li, Adv Crop Sci Tech 2016, 4:3 (Suppl)