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Molecular cell is the study of how molecules interact to give rise to the properties of cells, their ability to grow, maintain themselves and divide. Molecular Cell examines how the interaction of macromolecules gives rise to life, i.e., to the functioning of living organisms. The integration of molecular structure, function, and behaviour can lead to a functional living cell. The structural dynamics of domains within macromolecules and subunits of macromolecular assemblies, through the integration of pathways and organelles, to the interactions of a cell with its immediate environment are elucidated. The integration generates new functional properties through the nonlinear, dynamic and spatial nature of the interactions between biological macromolecules. The perturbations of molecular structures and their interactions cause malfunction and disease.
Gong Deuk Bae Effect of liquiritigenin on apoptotic beta-cell death by palmitate-induced lipotoxicity in INS-1 cells
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Dong-Kyu Kim Cross-Talk between Human Mast Cells and Epithelial Cells by IgE-mediated Periostin Production in Eosinophilic Nasal Polyps PPT Version | PDF Version
Thomas Böldicke Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells PPT Version | PDF Version
Gerald J Prud`homme Gamma-aminobutyric acid (GABA) treatment blocks inflammatory pathways and promotes survival and proliferation of pancreatic beta cells PPT Version | PDF Version
Eva M Carmona The inflammasome of activated human B-cellsregulates IL-1ò and IgM: A crosstalk between the innate and the adaptive immune response PPT Version | PDF Version
Jalil Mehrzd Bioluminescence-based detection of brain immune cells apoptosis and ATP depletion induced by aflatoxin B1 PPT Version | PDF Version
Jessy S Deshane Longitudinal changes in airway microbiome signatures and immunoregulatory cell dynamics following Bronchial Thermoplasty PPT Version | PDF Version
Bozena Futoma-Koloch C3 component deposition on Salmonella O48 cells characterized by sialylated lipopolysaccharide and different pattern of outer membrane proteins PPT Version | PDF Version
Amina Dahmani TRANSFORMING GROWTH FACTOR-ò PROGRAMS CENTRAL-MEMORY DIFFERENTIATION IN EX-VIVO STIMULATED HUMAN T CELLS BY MODULATING ID3 EXPRESSION PPT Version | PDF Version
Rongtuan Lin Modulating the Antioxidant Defences to Potentiate Oncolytic Virotherapy in Refractory Cancer Cells PPT Version | PDF Version
Moshe Giladi Tumor Treating Fields (TTFields) induced cancer cell death may be immunogenic resulting in enhanced antitumor efficacy when combined with immune-modulating therapy PPT Version | PDF Version
Daniel S Peiffer Dietary consumption of black raspberries or their anthocyanin constituents alters innate immune cell trafficking in esophageal cancer
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T. B. Karegoudar Purification and Characterization of Amidase from Paracoccus sp. SKG: Utilization of amidase inhibited whole cells for bioconversion of acrylonitrile to acrylamide PPT Version | PDF Version
Monray Edward Williams Molecular validation of putative antimicrobial peptides for improved Human Immunodeficiency Virus diagnostics via HIV protein p24 PPT Version | PDF Version
Gamal Wareth Investigation and molecular typing of Brucella isolated from dairy cattle herd immunized with Brucella abortus RB51 vaccine in Egypt PPT Version | PDF Version
Yosef Yarden Classically, the 3ââ¬â¢untranslated region (3ââ¬â¢UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3ââ¬â¢UTR alone, without all other elements in mRNA such as 5ââ¬â¢UTR and coding region. The importance of independent 3ââ¬â¢UTR RNA (referred as I3ââ¬â¢UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3ââ¬â¢UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3ââ¬â¢UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3ââ¬â¢UTR were important for its tumor suppression activity. Then, the C/EBP 3ââ¬â¢UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3ââ¬â¢UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3ââ¬â¢UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990ââ¬â¢s to 2000ââ¬â¢s, world scientists found several 3ââ¬â¢UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3ââ¬â¢UTR regions, although the existence of their transcribed products as independent 3ââ¬â¢UTR RNAs is still to be confirmed. Our studies indicate that the independent 3ââ¬â¢UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole. PPT Version | PDF Version
Fan-Gang Tseng Fan-Gang-Tseng-National-Tsing-Hua-University-Taiwan-Nano-Micro-fluidic-systems-for-circulating-Tumor-Cells-(CTCs)-rapid-detection-and-diagnosis PPT Version | PDF Version
Suoqin Tang Survivin siRNA nano particles are capable of inhibiting liver cancer cell growth both in vitro and in vivo PPT Version | PDF Version
Arshad mahmood TRANSPORT OF SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) ACROSS MUCUS AND CELLULAR INTERNALIZATION PPT Version | PDF Version
Kazuo Yano Regulatory approval for autologous human cells and tissue products in the United States, the European Union, and Japan PPT Version | PDF Version
Pi-Wan Cheng Disregulation of Golgi localization of glycosyltransferases alters mucin O-glycosylation and survival or metastatic properties of cancer cells PPT Version | PDF Version
Adel Nefzi ââ¬ÅAdel Nefzi-Torrey-Pines-Institute-for-Molecular-Studies-USA-Diversity-Oriented-Synthesis-of-low-Molecular-Weight-Acyclic-and-Heterocyclic-Compounds-from-Resin-bound-Polyamides-Application-for-Drug-Discoveryââ¬Â PPT Version | PDF Version
Christain Dani Human Induced Pluripotent Stem cells: A new source for brown and white adipocytes
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Carmen Alvarez-Dominguez A dendritic cell targeted vaccine loaded with a GAPDH peptide confers wide protection to listeriosis in susceptible and resistant mice
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Arghya Adhikary PEGylated-thymoquinone-nanoparticle mediated retardation of breast cancer cell migration by deregulation of cytoskeletal actin polymerization through miR-34a PPT Version | PDF Version
Paul A Beavis Adenosine receptor 2A blockade increases the efficacy of anti-PD-1 through enhanced anti-tumor T cell responses PPT Version | PDF Version
S Karthikeyan Resveratrol modulates expression of ABC transporters in non-small lung cancer cells: Molecular docking and gene expression studies PPT Version | PDF Version
Yamina Andre Nanostructured self-assembled P3HT thin films and their application to enhance organic solar cell efficiency PPT Version | PDF Version
Xuejun H Parsons Direct conversion of pluripotent human embryonic stem cells into functional human neuronal or cardiomyocyte cell therapy derivatives for regenerative medicine
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John S Pixley Generation of long-term human pancreatic islet cell activity in vivo by induction of immune tolerance to human stem cells PPT Version | PDF Version
Dinesh Keerty Efficacy and safety of low molecular weight heparin compared to unfractionated heparin for chronic outpatient hemodialysis in end stage renal disease: Systematic review and meta-analysis PPT Version | PDF Version
Dragos C Luca Anaplastic large cell lymphoma, ALK-positive, small cell variant, with leukemic presentation and rare CD8-positive phenotype PPT Version | PDF Version
Antonio Cilla Antiproliferative effect of main dietary phytosterols and/or ò-cryptoxanthin in human colon cancer Caco-2 cells through cytosolic Ca2+ - and oxidative stress-induced apoptosis PPT Version | PDF Version
Dele Ogunremi Strategy for developing a molecular sub typing tool for a food borne bacterial pathogen using a whole genome analysis approach: the case of Salmonella Enteritidis PPT Version | PDF Version
Aravind Jukanti Diversity analysis (genetic, molecular and gum content) of Cluster Bean (Cyamopsis tetragonoloba L.) - An emerging industrial crop PPT Version | PDF Version
Jack Sung Progenic Hair Regrowth Treatment: The Use of Platelet-Released Growth Factors for Treating Androgenetic Alopecia (AGA) by Activating Hair Follicle Stem Cells PPT Version | PDF Version
Rajasri Mandali Molecular characterization and management of Tomato leaf curl virus and its vector, B. tabaci, using cultural methods like guard crops and mulches in Tomato PPT Version | PDF Version
Kailash N Gupta Molecular characterization and phylogenetic analysis of Citrus mosaic Badna virus (CMBV) associated with Sathgudi sweet orange PPT Version | PDF Version
Chien-Fu Hung Mark cancer cells for CTL attack through coating with viral antigenic peptides CTLs kill tumor with viral peptides PPT Version | PDF Version
M.Krishnan Molecular cloning, expression, purification and functional characterization of 37 kDa Serine Protease from Bombyx mori PPT Version | PDF Version
Ofir Menashe The use of constructed nano and micro-filtration membrane as a confine bioreactor for microbial growth and extracellular digestive enzymes secretion PPT Version | PDF Version
Rajesh Kumar Vaid Isolation and molecular identification of Moraxella ovis and Moraxella spp. from Infectious Keratoconjunctivitis in sheep in India PPT Version | PDF Version
Rajib Deb Molecular characterization and identification of SNP at promoter region of bovine ITGB6 receptor gene PPT Version | PDF Version
Smith I Jaja L-Arginine supplementation enhances antioxidant activity and erythrocyte integrity in sickle cell anemia subjects PPT Version | PDF Version
Rafael Correa-Rocha HIV infection of Human regulatory T cells (Treg) downregulates Foxp3 expression and produces a loss of the suppressive capacity of these cells PPT Version | PDF Version
Marlous Dillingh Characterization of inflammation and immune cell modulation induced by lowdose LPS dose administration to healthy volunteers PPT Version | PDF Version
Ivan Mfouo-Tynga Effects of SulfonatedZinc Phthalocyanine and Low Intensity Laser Irradiation in Inducing Photodynamic Damagein Breast Cancer Cells
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Iqbal Parwez Genetic diversity and molecular declining population of four Channid species from North India and possible strategies PPT Version | PDF Version
Yuka Kobayashi Molecular design and electronic properties of new doping system: pure organic TTF-based salt-bridged crystals PPT Version | PDF Version
Stefanie Wienkoop Comprehensive Protein turnover analysis of a partial 15N stable isotope metabolic labelling experiment In Planta PPT Version | PDF Version
Ji-Zhong Bai Astrocytic contribution to deficient Ca2+ signalling and oxidative stress mediated by TRPV4 channels in A40-induced hippocampal cell death PPT Version | PDF Version
Eman H.Abdel-Rahman Induction of protective cellular and humoral responses against fasciolosis in rabbits using immunoaffinity fraction of Fasciola gigantica excretory secretory products PPT Version | PDF Version
Gerlies Treiber Vitamin D: Should a regular dose be part in immunomodulation of regulatory T cells in immunomediated diseases? PPT Version | PDF Version
Vincenza Dolo Critique in vitro analysis of platelet concentration effect on cells involved in in-vivo wound healing PPT Version | PDF Version
Paul H. Lerou Exploring human pluritotent stem cell heterogeneity using a multi-scale imaging and informatics pipeline PPT Version | PDF Version
Nguyen Linh Toan Molecular impacts of virus infections and genetic variants on the course of HBV-related liver diseases in Vietnam PPT Version | PDF Version
Paul J. Davis Nanotetrac targets the thyroid hormone receptor on integrin ñvò3 on tumor cells to promote apoptosis, disorder cell defense pathways and block angiogenesis PPT Version | PDF Version
Chin Chiew Foan Probing molecular and cellular mechanisms in tissue culture samples of commercial crops using Proteomic approach PPT Version | PDF Version
Vasiliki E. Kalodimou The effects of infused mesenchymal stem cells obtained by adipose tissue (ADSCs) to treat chronic scar tissue of the vocal cords in an animal model PPT Version | PDF Version
Miguel Rechichi Intraoperative in-vivo oct pachymetric mapping during epi-off pulsed accellerated high fluence corneal collagen cross-linking with dextran free riboflavin PPT Version | PDF Version
Maria Teresa Mascellino Candida bloodstream infections: species distribution and antifungal resistance in General Medicine wards and in Intensive Care Units (ICUs) PPT Version | PDF Version