ISSN: 2169-0170

Journal of Civil & Legal Sciences
Open Access

Justice Studies

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Justice Studies

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Citations : 266

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Justice Studies

Justice Studies is an interdisciplinary area of inquiry that brings together insights from the social sciences and humanities to explore questions of justice.

Related Journals of Justice Studies
Political Sciences & Public Affairs, Intellectual Property Rights, Sociology and Criminology, The Journal of Peace and Justice Studies, International Journal of Law, Crime and Justice, A Critical Journal of Crime, Law and Society

Justice Studies

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  • Muhamed Fakhri Omer
    Cathodoluminescence petrography for provenance studies of the sandstones of Ora Formation (Devonian-Carboniferous), Iraqi Kurdistan Region, Northern Iraq
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  • Yosef Yarden
    Classically, the 3’untranslated region (3’UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3’UTR alone, without all other elements in mRNA such as 5’UTR and coding region. The importance of independent 3’UTR RNA (referred as I3’UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3’UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3’UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3’UTR were important for its tumor suppression activity. Then, the C/EBP 3’UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3’UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3’UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990’s to 2000’s, world scientists found several 3’UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3’UTR regions, although the existence of their transcribed products as independent 3’UTR RNAs is still to be confirmed. Our studies indicate that the independent 3’UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
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    Ethnomedical studies of plants used for treatment of diseases in eastern part of Nigeria
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    Resveratrol modulates expression of ABC transporters in non-small lung cancer cells: Molecular docking and gene expression studies
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    Impact of rHu-Epo supplementation on CRF induced Neurobehavioral changes in rats: Studies on correlation with APP ratio, β amyloid and pTau expression
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    Cybercrime, Criminal Justice and the Funnel Effect: Challenges for Forensic Investigators, Prosecutors and Criminal Justice Officers
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    Studies on the Combined Effect of Multi – Walled Carbon Nano Tubes (MWCNTs) and Maleic Anhydride grafted Polypropylene (MA – g PP) on the Mechanical and Thermal Properties of Polypropylene (PP)
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    Preclinical studies of glucocorticoid receptor antagonists in the treatment of alcohol dependence
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    Laser [213-nm] depth-profiling studies of v/ni ratios in asphaltenes following liquid nitrogen pre-treatment
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    Parasitological and comparative pathological studies on monogenean infestation of cultured sea bream (Sparus aurata, Sparidae) in Egypt.
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    Recent structure relationship studies (SAR) on natural occurring sulfonium salts as potent -glucosidase inhibitors
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    Novel Concepts for the Application of Rapid DNA Technology as a Sentinel Event Prophylactic in the Criminal Justice System
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  • Jeffrey S Patrick
    High Performance Gas Chromatography Mass Spectrometry in Addressing the Challenges of Metabolomic Studies – Separation in Time and Mass
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    Discovery-based Targeted Proteomic Studies: Gel-based and/or off-gel protein sample preparation and purification
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    Elucidating the link between environment, nutrition, host immunity, AIDS and cancer as informed by selected studies in Kenya and beyond
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    Design, synthesis and antidiabetic, cardiomyopathy studies of cinnamic acid-amino acid hybrid analogs
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