ISSN: 2161-119X

Otolaryngology: Open Access
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  • Research Article   
  • Otolaryngol (Sunnyvale) 2017, Vol 7(6): 337
  • DOI: 10.4172/2161-119X.1000337

Therapeutic Applications and Benefits from Postsurgical Use of the Phytotherapeutic Bromelain in Otorhinolaryngology: A Non- Interventional Study

Reinhard Matschke1, Florian Zeman2, Gunnar Huppertz2, Michael Koller2 and Peter Meiser3*
1Ärztehaus Lindener Markt, Falkenstraße 27, 30449 Hanover, , Germany
2Center for Clinical Studies, , University Hospital Regensburg, 93042 Regensburg, Germany
3Ursapharm Arzneimittel GmbH, , Industriestraße 35, 66129 Saarbrücken, Germany
4, ‡BROHNO-2015 Study Consortium, Germany
*Corresponding Author : Peter Meiser, Ursapharm Arzneimittel GmbH, Industriestraße 35, 66129 Saarbrücken, Germany, Tel: +49 (0) 6805 9292 105, Fax: +49 (0) 6805 9292 87, Email: p.meiser@ursapharm.de

Received Date: Nov 24, 2017 / Accepted Date: Dec 05, 2017 / Published Date: Dec 12, 2017

Abstract

Background: Bromelain is a phytotherapeutic drug that is well established in medicinal use for the treatment of injuries and postoperative swelling. It is frequently recommended in otorhinolaryngological indications. However, there is lack of recent clinical data on its use in this setting.
Methods: We conducted a non-interventional study including 102 patients to evaluate postsurgical clinical (pain, edema, hematoma, signs of inflammation) and specific nasal symptoms (hindrance of nasal breathing, impairment of sleep, impairment of food intake, impairment of smell, impairment of taste). The participating physicians furthermore assessed the potential additional benefits of bromelain therapy.
Results: Clinical and specific nasal symptoms improved significantly during postoperative recovery and an additional benefit was assigned by the physicians given ratings in more than fifty percent of the documented cases. According to the physicians, the consumption of analgesics was “low” in seventy percent of the patients during adjunctive therapy with bromelain.
Conclusion: Given the good tolerability of bromelain treatment, this study substantiates its safe and efficacious use in otorhinolaryngological practice.

Keywords: Bromelain; Surgery; Otorhinolaryngology; Nose; Sinuses; Clinical trial

Citation: Matschke R, Zeman F, Huppertz G, Koller M, Meiser P (2017) Therapeutic Applications and Benefits from Postsurgical Use of the Phytotherapeutic Bromelain in Otorhinolaryngology: A Non-Interventional Study. Otolaryngol (Sunnyvale) 7:337. Doi: 10.4172/2161-119X.1000337

Copyright: © 2017 Matschke R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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