ISSN: 2161-119X

Otolaryngology: Open Access
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  • Case Report   
  • Otolaryngology 2014, Vol 4(2): 164
  • DOI: 10.4172/2161-119X.1000164

Synchronous HPV-Positive Squamous Cell Carcinoma of the Bilateral Base of the Tongue

Takatsugu Mizumachi1*, Tomohiro Sakashita1, Yusuke Hishimura1, Tomohiko Kakizaki1, Akihiro Homma1, Tomoko Mitsuhashi2 and Satoshi Fukuda1
1Department of Otolaryngology and Head and Neck Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan
2Department of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan
*Corresponding Author : Takatsugu Mizumachi MD, PhD, Department of Otolaryngology and Head and Neck Surgery, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan, Tel: +81-11-706-5958, Fax: +81-11-717-7566, Email: mizumati@med.hokudai.ac.jp

Received Date: Jan 12, 2014 / Accepted Date: Mar 18, 2014 / Published Date: Mar 25, 2014

Abstract

Although there have been several reports of synchronous Human Papillomavirus (HPV)-associated tonsillar carcinoma, no reports have shown synchronous HPV-associated Base of The Tongue (BOT) carcinoma. Here we discuss a case of synchronous HPV-associated BOT carcinoma and review the literature concerning HPV-associated second primary tumors. We report the case of a 59-year-old man with synchronous HPV-positive Squamous Cell Carcinoma (SCC) of the bilateral BOT. Both BOT SCCs were positive for HPV16. The patient received concomitant cisplatin radiotherapy, and remains disease-free at 18 months post-treatment.

Keywords: HPV, Base of tongue, Synchronous, Squamous cell carcinoma

Citation: Mizumachi T, Sakashita T, Hishimura Y, Kakizaki T, Homma A, et al. (2014) Synchronous HPV-Positive Squamous Cell Carcinoma of the Bilateral Base of the Tongue. Otolaryngology 4:164. Doi: 10.4172/2161-119X.1000164

Copyright: © 2014 Mizumachi T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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