Abstract

The gold standard for determining static and dynamic bone morphological parameters and tumor burden in bone is currently bone biopsy with a 7–8 mm “Bordier” trephine of trans-iliac bone. However, in clinical practice, the size of the needle is rarely, if ever, used because it is a concern for both patients and doctors. Our team has previously assessed tumor receptors with 2 mm trephine needles and compared tumor cell yield between 2 mm iliac crest biopsies and CTguided specimens.