Abstract

The emergence of SARS-CoV-2 has led to a global pandemic, with significant morbidity and mortality primarily attributed to respiratory complications. However, mounting evidence suggests that SARS-CoV-2 can also affect the central nervous system (CNS), leading to a spectrum of neurological manifestations. This article reviews the neurovirulent, neurotropic, and neuroinvasive properties of SARS-CoV-2, elucidating the mechanisms underlying its interaction with the nervous system and the associated neurological complications in COVID-19 patients. Understanding these mechanisms is crucial for developing targeted therapeutic strategies and mitigating neurological morbidity in affected individuals