Abstract

Pain management is a critical aspect of healthcare, and while opioids have been a cornerstone of pain relief, their use is increasingly scrutinized due to concerns about addiction, overdose, and side effects. This article provides a comprehensive review of non-opioid pain relief strategies, including pharmacological and non-pharmacological approaches. It explores the efficacy, mechanisms, and clinical applications of various non-opioid therapies and discusses their role in multimodal pain management.