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Research Article

Maternal Hemoglobin, Preterm Pains, Failure of Tocolysis, Preterm Birth, Small for Gestational Age Neonate

Chhabra S* and Chopra S
Department of Obstetrics and Gynaecology, Mahatma Gandhi Institute of Medical Sciences, India
*Corresponding Author : Chhabra S
Department of Obstetrics & Gynaecology
Mahatma Gandhi Institute of Medical Sciences
Sevagram, 442102, Wardha, Maharashtra, India
Tel: 917152284645
E-mail: schhabra@mgims.ac.in
Received date: Feb 26, 2016; Accepted date: Mar 21, 2016; Published date: Mar 26, 2016
Citation: Chhabra S, Chopra S (2016) Maternal Hemoglobin, Preterm Pains, Failure of Tocolysis, Preterm Birth, Small for Gestational Age Neonate. J Preg Child Health 3:235. doi:10.4172/2376-127X.1000235
Copyright: © 2016 Chhabra S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Small for gestational age (SGA) babies have higher perinatal mortality, morbidity, sequelae. Iron deficiency anaemia in mother significantly increases SGA. Objective: To know relationship between SGA neonate, preterm pains, preterm births with anaemia in mother. Material methods: Analysis of case records of primigravida who delivered single live SGA baby, with equal controls (appropriate for gestational age) over 5 years. Results: Of 27,984 who delivered, 1500 (5.36%) were study subjects, as per inclusion, exclusion 1190 (79.3%) were anaemic, 1002(66.8%) controls anaemic, significant difference. Amongst study 41.8% (628) were mildly, 33.6% (505) moderately, 3.8% (57) severely anaemic, 20.7% nonanaemic, 620 (41.3%) controls, mildly 352(23.5%), moderately 30(2%), severely anaemic, 33.2% nonanaemic. Most study, controls were of 20-29 years. Significantly more nonanaemic study cases were labourers (9.6%), compared to controls (2.6%). With SGA baby, risk of preterm birth increasing with severity of anaemia. Of 50, (8.0%) with mild anaemia SGA babies, who had preterm pains, tocolytics were able to arrest birth in 12%.Preterm births were 7.2% in nonanaemic, 5.5% mildly anaemic, 14.5% moderatly,43.9% severe (p < 0.05). Preterm birth arrest by tocolytics decreased from 22.7% without anaemia to 16.7% with severe, 12% with mild, 8.8% moderate anaemia (p < 0.05). Amongst study subjects, 21(3.3%) with mild anaemia, 17(3.4%) moderate anaemia, 10(17.5%) severe anaemia, 9(2.9%) nonanaemiac had birth weight 1000-1499 gms., 142(22.6%) with mild anaemia, 276(54.6%) moderate anaemia,47(82.5%) severe anaemia, 8(2.6%) with no anaemia had weight 1500-1999 gms. 465(74.1%) with mild anaemia, 212 (42%) moderate anaemia, 293 (94.5%) no anaemia had weight 2000-2499 gms. MBW decreasing with increasing severity of anaemia.

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