Abstract

After the surgical insertion of biomaterial implants, biomaterial-associated infections might happen at any moment and lower their success rates. On-demand antimicrobial release coatings have been developed, however there are no in vivo release triggers specifically related to illness, and accidental antimicrobial leaking can deplete a coating before it is needed. In this instance, we affix magnetic nanoparticles to a biomaterial surface that may be removed in a magnetic field via an infectious biofilm that is clinging to the surface. After being exposed to PBS, magnetic nanoparticles stayed firmly adhered to a surface for at least 50 days. They did not encourage bacterial adherence or have a detrimental impact on interactions with adherent tissue cells.