Abstract

Interleukin-14 (IL-14), originally characterized for its involvement in B cell biology, has emerged as a multifaceted cytokine with profound immunomodulatory properties. Its dualistic nature, exerting both pro-inflammatory and immunoregulatory effects, positions IL-14 as a promising frontier in immune therapy. This abstract explores the diverse functions of IL-14 and its therapeutic implications in cancer immunotherapy and autoimmune diseases. By elucidating the intricate mechanisms underlying IL-14-mediated immune regulation and developing targeted therapeutic strategies, we aim to harness its potential for advancing precision medicine and improving patient outcomes in diverse disease settings.