Abstract

Pain is a multifaceted experience shaped by genetic predispositions and epigenetic influences. This case delves into how these factors converge in a 45-year-old woman grappling with chronic lower back pain. Genetic variations, such as polymorphisms in pain-related genes, and epigenetic changes, like DNA methylation patterns, contribute uniquely to pain perception and treatment response. By unraveling these complexities, clinicians can tailor interventions that align with each patient's genetic blueprint and epigenetic profile. This approach not only enhances our comprehension of pain mechanisms but also holds promise for advancing personalized strategies that alleviate suffering and improve quality of life for individuals enduring chronic pain conditions.