Abstract

Yeast, particularly Saccharomyces cerevisiae, has been a cornerstone in biotechnology, contributing significantly to the production of biofuels, pharmaceuticals, and industrial chemicals. Recent strides in biotechnological research have unveiled the immense potential of cell surface engineering as a transformative strategy to enhance the functionality and versatility of yeast strains. This innovative approach involves tailoring the outer layer of yeast cells, offering a gateway to novel applications and improved performance. Various strategies constitute yeast cell surface engineering, including display systems, glycoengineering, incorporation of cellulosic binding modules, and synthetic biology approaches. These techniques enable the precise manipulation of cell surface properties, influencing substrate utilization, product formation, and interactions with the environment.