ISSN: 2155-952X

Journal of Biotechnology & Biomaterials
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Short Communication   
  • J Biotechnol Biomate 2022 12:300,

Calcium Phosphate Biomaterials Osteoinduce Bone in Small Animals

Hong Yue*
Department of Immunology, Sichuan University, China
*Corresponding Author : Hong Yue, Department of Immunology, Sichuan University, China, Email: yue.3@gmail.com

Received Date: Sep 02, 2022 / Published Date: Oct 14, 2022

Abstract

Despite the fact that the osteoinduction mechanism of calcium phosphate (CP) ceramics is yet unknown, a number of crucial characteristics, including chemical composition, pore size and porosity, have been described. In this work, mice's leg muscles and rabbits' dorsal muscles were implanted with calcium phosphate powder, biphasic calcium phosphate ceramic powder (BCP, group 2), and entire BCP rods (group 3). For biological and histological investigation, samples were taken one month and three months following implantation. At the third month, mice showed new bone tissues in 9/10 samples in group 3, 3/10 samples in group 2, and 10/10 samples in group 1, but not in rabbits. Osteogenic differentiation was seen when human mesenchymal stem cells (hMSCs) were cultivated in vitro with traces of CaP and BCP powder. Our findings suggested that pore structure would promote increased bone formation and that chemical composition is a prerequisite for osteoinduction.

Citation: Yue H (2022) Calcium Phosphate Biomaterials Osteoinduce Bone in Small Animals. J Biotechnol Biomater, 12: 300.

Copyright: © 2022 Yue H. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Top