Fibromyalgia: Open Access
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  • Case Report   
  • Fibrom open 2016, Vol 1(1): 106

Bupropion Use for Adjuvant Analgesia in a Patient with Fibromyalgia: A Case Report

Adam Gummersheimer1, Tabetha Todd1 and Christopher M. Herndon2*
1Southern Illinois University, Edwardsville, 200 University Park Drive, Box 2000, Edwardsville, USA
2Associate Professor, School of Pharmacy, Advanced Practice Pharmacist, Scott Air Force Base, Southern Illinois University, Edwardsville, 200 University Park Drive, Box 2000, Edwardsville, USA
*Corresponding Author : Christopher M. Herndon, Associate Professor, School of Pharmacy, Advanced Practice Pharmacist, Scott Air Force Base, Southern Illinois University, Edwardsville, 200 University Park Drive, Box 2000, Edwardsville, USA, Tel: 618-420-9886, Email: cherndo@siue.edu

Received Date: Jan 08, 2016 / Accepted Date: Feb 28, 2016 / Published Date: Mar 02, 2016

Abstract

Fibromyalgia is a chronic syndrome characterized by widespread pain, fatigue, gastrointestinal disturbances, neurocognitive dulling, and insomnia. Currently, three medications are approved for fibromyalgia by the United States Food and Drug Administration (FDA): pregabalin, duloxetine, and milnacipran. This case study reviews the use of bupropion as a potential co-analgesic in patients with refractory fibromyalgia. Previous studies have assessed the use of dopamine agonists in the treatment of fibromyalgia with both ropinirole and pramipexole exhibiting efficacy. Bupropion, an atypical antidepressant with noradrenergic and dopaminergic modulatory effects, may theoretically provide similar efficacy in patients with fibromyalgia syndrome.

Keywords: Bupropion; Fibromyalgia; Dopamine; Adjuvant analgesia

Citation: Gummersheimer A, Todd T, Herndon CM (2016) Bupropion Use for Adjuvant Analgesia in a Patient with Fibromyalgia: A Case Report. Fibrom Open Access 1: 106.

Copyright: ©2016 Gummersheimer A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Review summary

  1. Joshua Williams
    Posted on Aug 30 2016 at 11:44 am
    This is a nice review and case report from a pharmacological perspective. This case report related to buprion use for the treatment of fibromyalgia is complicated by the adjustment of multiple drugs, no pre-post assessment tool related to depression or anxiety and overall minimal improvement. The finding that there might be improvement of cognitive and morning symptoms are really enough to suggest that further studies are warranted.
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