Abstract

Addiction, whether to drugs, alcohol, tobacco, or certain behaviors, represents a complex interplay between genetic, environmental, and neurobiological factors. Advances in neurobiology have significantly enhanced our understanding of the underlying mechanisms driving addiction, providing insights that are transforming treatment approaches. This manuscript reviews the application of neurobiological research in the treatment of various addictions, discussing how neurobiological findings inform the development of novel therapeutic strategies. We explore the role of neurotransmitter systems, brain circuits, and genetic predispositions in addiction and evaluate current and emerging treatment modalities, including pharmacotherapy, behavioral interventions, and neurostimulation techniques