ISSN: 2155-6199

Journal of Bioremediation & Biodegradation
Open Access

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  • Mini Review   
  • JBRBD,
  • DOI: 10.4172/2155-6199.1000541

A Two-Phase and Long-Lasting Multi-Antibacterial to Prevent Implants-Related Infections

Agata Wojcik*
Department of Biochemistry and Biotechnology, University of Medical Lubin, Poland
*Corresponding Author : Agata Wojcik, Department of Biochemistry and Biotechnology, University of Medical Lubin, Poland, Email: AgataWojcik74@gmail.com

Received Date: Nov 03, 2022 / Accepted Date: Nov 30, 2022 / Published Date: Nov 30, 2022

Abstract

In clinical practise, bacterial infection and aseptic loosening pose the biggest obstacles to titanium implant placement and significantly lower the survival rate of implants. The infection peak period for implants is the first four weeks following surgery. For an implant to be successful, it is crucial to prevent bacterial adhesion and growth during the initial stages as well as to encourage subsequently occurring osteointegration. Here, using a modified layer-bylayer method and dopamine polymerization, we created a quaternary ammonium carboxymethyl chitosan, collagen, and hydroxyapatite multilayer coating on Ti substrates. HAP coating demonstrated a two-phase function and several antibacterial properties. The covalently bound QCMC showed both contact-killing and release-killing properties during the infection peak phase at the first four weeks postoperatively; the second stage involves osteogenesis [1].

Citation: Wojcik A (2022) A Two-Phase and Long-Lasting Multi-Antibacterial to Prevent Implants-Related Infections. J Bioremediat Biodegrad, 13: 541. Doi: 10.4172/2155-6199.1000541

Copyright: © 2022 Wojcik A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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