Vitamin B3 and Its Derivatives? Modulatory Effects on the Levels of Cytoskeletal Proteins, Apoptotic and Vascular Regulators, and Diabetic Rat Brain as Indicators of Neuroprotection
Received Date: Dec 01, 2023 / Published Date: Dec 27, 2023
Abstract
Animal models of diabetes mellitus (DM) have previously demonstrated the beneficial effects of nicotinamide (NAm) and its derivatives; however, the mechanisms underlying these effects’ neuroprotective properties remain largely unclear. The current study set out to determine whether NAm and the conjugate of nicotinic acid with gamma-aminobutyric acid (N-GABA) could alter the expression levels of molecules linked to angiogenesis, certain cytoskeletal proteins, and regulators of apoptosis in the brains of diabetic rats
Citation: Perwin H (2023) Vitamin B3 and Its Derivatives’ Modulatory Effectson the Levels of Cytoskeletal Proteins, Apoptotic and Vascular Regulators, andDiabetic Rat Brain as Indicators of Neuroprotection. Biopolymers Res 7: 190.
Copyright: © 2023 Perwin H. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
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