Abstract

Nanomaterials are employed extensively in a variety of industries, particularly in biomedicine and stem cell therapy. However, the potential hazards connected to the use of nanomaterials are also gradually rising. To assess the developmental toxicity of nanomaterials, effective and reliable toxicological models are essential. Developmental toxicity has a new perspective thanks to advances in stem cell research. To examine the harmful effects and hazardous mechanisms, numerous researchers have recently actively investigated the impacts of nanomaterials on diverse stem cells, including adult stem cells and embryonic stem cells (ESCs). In this review, we outlined how nanomaterials affect ESC, mesenchymal stem cell, and neural stem cell proliferation and differentiation. Additionally, we talked about the benefits of stem cells in nanotoxicology.

Keywords: Stem cells; Nanotoxin; Nanomaterials application