Journal of Gastrointestinal & Digestive System
Open Access

Review Article

Updates in Drug Development Strategies against Peptic ulcer

BB Subudhi^1*, SP Sahoo² and PK Sahu¹

¹School of pharmaceutical Science, Siksha O Anusandhan University, Bhubaneswar, Orissa, 751003, India

²Research Center-II, Aurobindo Pharma Limited, Hyderabad, India

Corresponding Author:

BB Subudhi
Associate Professor, Siksha O Anusandhan University School of Pharmaceutical Sciences
School of Pharmaceutical Sciences, Ghatikia, Kalinganagar, Bhubaneswar, 751003, India
Tel: 919853945363
E-mail: bharatbhusans@gmail.com

Received Date: September 16, 2015 Accepted Date: February 26, 2016 Published Date: March 4, 2016

Citation: Subudhi BB, Sahoo SP, Sahu PK (2016) Updates in Drug Development Strategies against Peptic ulcer. J Gastrointest Dig Syst 6:398. doi:10.4172/2161-069X.1000398

Copyright: © 2016 Subudhi BB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Traditional use of antacids and use of histamine inhibitors have become ineffective in the management of peptic ulcer. Irreversible inhibition of proton pump although reduces ulceration, in the long run leads to adverse issues. It has not been possible to develop an ideal proton pump inhibitor. In this scenario, search for alternatives by capitalizing on the multifactorial etiology of ulceration holds promise.

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